Although 25-hydroxyvitamin D (25-OHD)-l-hydroxylase and -24-hydroxylase have been measured extensively in fowl, no methods for assay of these enzymes have been validated for the mammal. Inhibitory activity present in all mammalian tissues is a hindrance to accurate measurement The mechanism by which protein components from rat tissues reduce chick 25OHDS-1-hydroxylase activity were studied by a...

Studies were performed to further characterize the male-specific hepatic recombinant microsomal vitamin D 25-hydroxlase CYP2C11, expressed in baculovirus-infected insect cells, and determine whether it is also a vitamin D 24-hydroxylase. 25- and 24-hydroxylase activities were compared with those of 10 other recombinant hepatic microsomal cytochrome P-450 enzymes expressed in baculovirus-infecte...

The synthesis of imidazole styrylbenzamide, tert-butyl styrylimidazole, and tert-butyl styrylsulfonate derivatives is described. Evaluation of binding affinity and inhibitory activity against CYP24A1 identified the imidazole styrylbenzamides as potent inhibitors of CYP24A1, having selectivity with respect to CYP27B1 comparable with or greater than that of the standard ketoconazole. Further eval...

an experiment was conducted to study the effects of dietary levels of extruded full fat soybean (effsb) on performance, blood metabolites and intestinal morphology of broiler chickens. a batch of ffsb was wet extruded at 155 °c, 15 seconds to provide the extruded full fat soybean (effsb) sample. one hundred and forty four d-old ross 308 male broiler chicks were divided into 12 groups with 12 bi...

Argentatin B is a naturally occurring tetracyclic triterpene isolated from Parthenium argentatum x P. tomentosa. It was microbiologically transformed to 16, 24-epoxycycloartan-3alpha, 25-diol, (isoargentatin D), by Nocardia corallina var. taoka ATCC 31338, Mycobacterium species NRRL B3683 and Septomyxa affinis ATCC 6737. The later microbe also produced 16, 24-epoxycycloartan-3beta, 25-diol (arg...

An experiment was carriedout to investigate the effect of dietary energy level levels on feed intake modern broiler chickens during growth period. A total 160 Ross chicks (mixed-sex) in a completely randomized design with 4 treatments and replicates (10 birds) were used. The fed from 11 24 days age treatments, including grower diets 2800, 2900, 3000, 3100 kcal/kg ME constant nutrient ratios. Al...

The aim of this experiment was to assess the effects of using saturated fatty acid (SFA) and some unsaturated fatty acid (UFA) sources in finishing period on performance, fat deposition and blood metabolites of broiler chickens. One hundred and forty four 28-d old male broiler chickens were randomly assigned to 4 treatments and 6 replicates in a completely randomized design. Four isocaloric/iso...