To understand the day-to-day pathophysiology of impaired muscle glycogen storage in type 2 diabetes, glycogen concentrations were measured before and after the consumption of sequential mixed meals (breakfast: 190.5 g carbohydrate, 41.0 g fat, 28.8 g protein, 1253 kcal; lunch: 203.3 g carbohydrate, 48.1 g fat, 44.0 g protein, 1497.5 kcal) by use of natural abundance (13)C magnetic resonance spe...

A 3 × 2 factorial experiment was conducted to investigate the effects of different ratios of dietary laminarin (LAM) and fucoidan (FUC) on growth performance and nutrient digestibility in newly weaned piglets. At weaning, 168 piglets (24 d of age; 6.8 kg live weight) were assigned to 1 of 6 dietary treatments (n = 14/treatment): (i) basal diet, (ii) basal diet + 240 mg/kg FUC, (iii) basal diet ...

The pharmacokinetics of cefoperazone were evaluated in 25 infants (mean age, 26 days) after intramuscular and intravenous routes of administration. The levels in blood that were achieved were severalfold higher than those required to inhibit common pathogens. The mean half-life of 240 min was one-half of that observed in 1- to 2-day-old infants but about twice that seen in adults. Further evalu...

The variations of stratospheric ozone and UVB observed at ground were compared with those solar indices. During sequences 27-day oscillations, X-ray had very large amplitudes (exceeding 50%), EUV near 30 nm ~20%, Lyman alpha 121.6 ~10%, Mg II 280 ~5%, continua 180-210 ~2%, 210-240 ~1.5%, 240-300 ~1%, 300-350 ~0.5%. There distinct peaks seen in all these, spacing roughly about 27 days. For effec...

To investigate the effect of irrigation and urea levels on some agronomic traits essential oil content pot marigold, a study was conducted in split-plot based completely randomized block design with three replications. The treatments included four (irrigation after 5, 10, 15, 20 days) nitrogen (0, 80, 160, 240 kg ha-1 urea). plant height, flower number, dry weight, number seeds/head, thousand k...

Received for publication, October 19, 1949. lowing: (a) 20-mg. pellets of diethylstilbestrol,1 im planted subcutaneously on the 49th or the 68th day of life, with the animals killed 90, 120, 150, 170, 180, 217, 240, 270 or 300 days later; (6) the same, except the pellets contained diethylstilbes trol and cholesterol in a ratio of 1:4 and were im planted on the 53rd day of life; (c) 0.6 mg. of d...

We tested the hypothesis that endothelial dysfunction induced by angiotensin II (Ang-hypertension) would impair regulatory control of vascular smooth muscle L-type Ca channels by endothelial nitric oxide synthase (eNOS). We studied cerebral lenticulostriate arterioles (LSAs) from control rats, from rats infused with Ang (240 g · kg 1 · h 1 SQ 4 days), which were normotensive, and from Ang-hyper...

This paper outlines how our highly efficient, power-aware supercomputer called Green Destiny and our open-source parallelization of BLAST called mpiBLAST combine to create a bit of “bioinfomagic.” Green Destiny, featured in The New York Times and winner of a 2003 R&D 100 Award, revolutionized high-performance computing by re-defining performance to focus on issues of efficiency, reliability, an...

We tested the hypothesis that endothelial dysfunction induced by angiotensin II (Ang-hypertension) would impair regulatory control of vascular smooth muscle L-type Ca2+ channels by endothelial nitric oxide synthase (eNOS). We studied cerebral lenticulostriate arterioles (LSAs) from control rats, from rats infused with Ang (240 microg x kg(-1) x h(-1) SQ x4 days), which were normotensive, and fr...