The Agilent 7000 GC/QQQ system can provide both high selectivity and high sensitivity for the analysis of drugs. Low-level detection and confirmation of large numbers of target drugs in blood extracts is possible in a single run. Combined with information from a single quadrupole screening instrument like the Agilent GC/NPD/MSD/DRS system, a much more complete picture of each sample is now poss...

Moore and Sęk [J. Acoust. Soc. Am. 125, 3186-3193 (2009)] measured discrimination of a harmonic complex tone and a tone in which all harmonics were shifted upwards by the same amount in Hertz. Both tones were passed through a fixed bandpass filter and a background noise was used to mask combination tones. Performance was well above chance when the fundamental frequency was 800 Hz, and all audib...

The crystal structure o f the title com pound was determ ined to obtain structural inform ation on asym metric tetrapyrroles bearing an sp3-hybridized meso-oxygen atom . These types o f com pounds serve as models for the enol-form o f oxophlorins, which often are obtained in crystalline form only w ith ro tational disordering o f the oxofunction, m aking conform ational analyses difficult. C37H...

The pharmacokinetics of trimethoprim-sulfamethoxazole were studied in 12 healthy adult subjects receiving trimethoprim at 20 mg/kg of body weight per day and sulfamethoxazole at 100 mg/kg/day, which is the conventional dose for treating Pneumocystis carinii pneumonia (PCP). Daily doses were evenly divided and orally administered every 6 h for 3 days. Trimethoprim, sulfamethoxazole, and N4-acety...