Abstract The Stimulator of Interferon Genes (STING) plays an important role in innate immunity by inducing type I interferons response to sensing viral or bacterial cytosolic DNA. Cyclic dinucleotides (CDNs) are known activate STING. Here, we describe the synthesis and biological evaluation two new 3’,3’‐CDN, which internucleotide linkages were replaced, respectively, a 1,2,3‐triazole moiety (a...

The equilibrium adsorption of bovine serum albumin (BSA) on poly-3-hydroxybutyrate (PHB) and poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) surfaces was studied at different solution concentrations. data were fitted to the Langmuir Freundlich models. protein behaviour further investigated by analysing conformation surface adsorbed BSA using Fourier transform infrared (FTIR) spectroscopy wi...