Vogiagis, Daphne, Eric M. Glare, Aileen Misajon, Wendy Brown, and Paul E. O’Brien. Cyclooxygenase-1 and an alternatively spliced mRNA in the rat stomach: effects of aging and ulcers. Am J Physiol Gastrointest Liver Physiol 278: G820–G827, 2000.—Prostaglandins play a critical role in gastric mucosal cytoprotection and decrease progressively with age. Cyclooxygenase (COX), the rate-limiting enzym...

Horowitz, Jeffrey F., and Samuel Klein. Whole body and abdominal lipolytic sensitivity to epinephrine is suppressed in upper body obese women. Am J Physiol Endocrinol Metab 278: E1144–E1152, 2000.—We measured whole body and regional lipolytic and adipose tissue blood flow (ATBF) sensitivity to epinephrine in 8 lean [body mass index (BMI): 21 6 1 kg/m2] and 10 upper body obese (UBO) women (BMI: ...

ITE JOURNAL / SEPTEMBER 2003 RAIL FREIGHT TRANSPORT IN EUROPE—TIME FOR A CHANGE While transport in Europe has grown at an annual rate of 2.5 to 3 percent over the last 20 years, rail transport has experienced a significant decline. This process may be appreciated by comparing figures from 1970 and 1999: In 1970, railway market share in the European Union (EU) was registered at 21 percent. By 19...

Buettner, Roland, Christopher B. Newgard, Christopher J. Rhodes, and Robert M. O’Doherty. Correction of diet-induced hyperglycemia, hyperinsulinemia, and skeletal muscle insulin resistance by moderate hyperleptinemia. Am. J. Physiol. Endocrinol. Metab. 278: E563–E569, 2000.— Human obesity and high fat feeding in rats are associated with the development of insulin resistance and perturbed carboh...

CHUL-HEE KIM,1 JANG H. YOUN,2 JOONG-YEOL PARK,3 SUNG K. HONG,3 KYONG S. PARK,4 SUNG W. PARK,5 KYO I. SUH,1 AND KI-UP LEE3 1Department of Internal Medicine, Soonchunhyang University College of Medicine, Seoul 140-743; 3University of Ulsan College of Medicine, Seoul 138-736; 4Seoul National University College of Medicine, Seoul 110-744; and 5Hallym University College of Medicine, Anyang 431-070, ...

Leser, J., M. F. Beil, O. A. Musa, G. Adler, and M. P. Lutz. Regulation of adherens junction protein p120ctn by 10 nM CCK precedes actin breakdown in rat pancreatic acini. Am. J. Physiol. Gastrointest. Liver Physiol. 278: G486–G491, 2000.—The initial pathophysiological events that characterize CCK-hyperstimulation pancreatitis include the breakdown of the actin filament system and disruption of...

Zimmermann, Ellen M., Lina Li, Eileen C. Hoyt, Jolanta B. Pucilowska, Steven Lichtman, and P. Kay Lund. Cell-specific localization of insulin-like growth factor binding protein mRNAs in rat liver. Am. J. Physiol. Gastrointest. Liver Physiol. 278: G447–G457, 2000—The liver is a major source of circulating insulin-like growth factor I (IGFI), and it also synthesizes several classes of IGF binding...

ITE JOURNAL / AUGUST 2001 BACKGROUND High speeds and rapidly increasing vehicle volumes characterize many of America’s rural, two-lane highways. These features, combined with midto shortradius horizontal curves and limited sight distances, can create hazardous road conditions for the motoring public. These highways may or may not exhibit high accident numbers or rates but are often described by...

Mundinger, Thomas O., and Gerald J. Taborsky, Jr. Differential action of hepatic sympathetic neuropeptides: metabolic action of galanin, vascular action of NPY. Am. J. Physiol. Endocrinol. Metab. 278: E390–E397, 2000.—Activation of hepatic nerves increases both hepatic glucose production (HGP) and hepatic arterial vasoconstriction, the latter best described by a decrease of hepatic arterial con...

Ma, L., W. P. Wang, J. Y. C. Chow, S. T. Yuen, and C. H. Cho. Reduction of EGF is associated with the delay of ulcer healing by cigarette smoking. Am. J. Physiol. Gastrointest. Liver Physiol. 278: G10–G17, 2000.—Cigarette smoking is associated with peptic ulcer diseases. Smokers have lower levels of salivary epidermal growth factor (EGF) than nonsmokers. We investigated whether reduction of EGF...