A highly enantioselective carboalkoxylation of alkynes catalyzed by cationic (DTBM-MeO-Biphep)gold(I) complexes is reported. Various optically active β-alkoxyindanone derivatives were obtained in good yields with high enantioselectivities. Furthermore, this methodology was extended to the enantioselective synthesis of 3-methoxycyclopentenones. The reaction is proposed to proceed through an enan...

We argue the importance both of developing simple sufficient conditions for the stability of general multiclass queueing networks and also of assessing such conditions under a range of assumptions on the weight of the traffic flowing between service stations. To achieve the former, we review a peak-rate stability condition and extend its range of application and for the latter, we introduce a g...

[This corrects the article on p. 466 in vol. 7, PMID: 27790158.].

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BACKGROUND Previously, we reported on the unexpected development of distant metastases in the subcutaneous rat pancreas CA20948 tumor model after 4.5 weeks of treatment with RAD001-only or in combination with [(177)Lu-DOTA(0),Tyr(3)]octreotate ((177)Lu-DOTATATE) (Cancer Res. 73:12-8, 2013). Moreover, the combination therapy was less effective compared to (177)Lu-DOTATATE-only. In the current st...

BACKGROUND scVEGF/(177)Lu is a novel radiopharmaceutical targeted by recombinant single-chain (sc) derivative of vascular endothelial growth factor (VEGF) that binds to and is internalized by vascular endothelial growth factor receptors (VEGFR). scVEGF/(177)Lu potential as adjuvant and neoadjuvant anti-angiogenic therapy was assessed in metastatic and orthotopic mouse models of triple-negative ...

© SINPE-GASAPE ABSTRACT: Background: Abdominal catastrophe, suture leakage and wound dehiscence are serious complications of surgical procedures. Wound infection is a frequent complication and the mortality is high due to long and difficult treatment procedures. Treatment is often difficult as a result of fistula formation, presence of necrotic and infected tissue, and complex surgical manageme...

s Service Registry No. 000919302) based on the weight of the

1. The structure of one class of giant tangential neurons in the lobula plate of Calliphora, the `Vertical System (VS)' has been investigated by light microscopy. Different staining and reconstruction procedures were employed to ensure that all existing VS-neurons are revealed. 2. There are 11 VS-cells in a characteristic, and constant arrangement (Fig. 2). Each cell covers a particular area of...