The extract of licorice (Glycyrrhiza glabra L.) has been widely used for many centuries in the traditional Chinese medicine as native anti-allergic agent. Glycyrrhizin (GL), a triterpenoid-saponin, extracted from the roots of licorice is the most effective compound for inflammation and allergic diseases in human body. The biological and pharmacological studies revealed that GL possesses many ph...

The use of solutions containing carboxymethyl-beta-cyclodextrin (CMCD) or CaCl2 for enhancing the removal of Hg from a sandy soil was investigated using batch and column experiments. The retention of Hg appeared to be controlled by specific adsorption reactions, which greatly constrained Hg removal when using water (KNO3 solution) to flush columns packed with contaminated soil. The results show...

Problem statement: In today’s scenario, microalgae are widely recognized as a promising source for biofuel production as a renewable source of energy. They are exceedingly rich in oil, which can be converted to biofuel. This paper deals with one of the method to enhance the lipid content in microalgae. Approach: Microalga, Chlorella pyrenoidosa, was grown autotrophically in batch culture and th...

In this investigation, a novel temperature-pH responsive copolymer was prepared by the radical copolymerization between 2-hydroxypropyl acrylate (HPA) and aminoethyl methacrylate hydrochloric salt (AMHS). The molecular structure of the corresponding copolymer has been confirmed by 1H NMR and FTIR measurements. The results indicated that the lower critical solution temperature (LCST) of the resu...

We have previously reported on the inhibitory effect of Glycyrrhizae radix (Gl radix) on mouse endometrial carcinogenesis. The present study was performed to clarify the effects of Gl radix and glycyrrhizin (GL), the main part of Gl radix, on estradiol (E2)-related endometrial carcinogenesis. Both Gl radix and GL exerted a significant decrease in the COX-2, IL-1alpha and TNF-alpha mRNA expressi...

BACKGROUND The aim of this study is to investigate the hematological manifestations of human immunodeficiency virus (HIV) infection, the risk factors for cytopenia, and the effect of highly active anti-retroviral therapy (HAART) on cytopenia. METHODS Medical records of patients treated for HIV at the Seoul National University Hospital from January 2005 to March 2010 were retrospectively revie...

Herpesvirus glycoprotein complex gH/gL provides a core entry function through interactions with the fusion protein gB and can also influence tropism through receptor interactions. The Epstein-Barr virus gH/gL and gH/gL/gp42 serve both functions for entry into epithelial and B cells, respectively. Human cytomegalovirus (HCMV) gH/gL can be bound by the UL128-131 proteins or gO. The phenotypes of ...

Human cytomegalovirus (HCMV) is a ubiquitous virus that is a major pathogen in newborns and immunocompromised or immunosuppressed patients. HCMV infects a wide variety of cell types using distinct entry pathways that involve different forms of the gH/gL glycoprotein: gH/gL/gO and gH/gL/UL128-131 as well as the viral fusion glycoprotein, gB. However, the minimal or core fusion machinery (suffici...