The hydrophobically assisted switching phase (HASP) method was applied in the assembly of oligomannosides. A new mannosyl donor with high reactivity was selected after a series of optimization studies, which was suitable for the synthesis of oligomannosides via the HASP method. The practicability of the HASP method towards the synthesis of branched oligosaccharides was explored and two branched...

Since the industrial revolution ushered in the economic benefits of similarity, standardization has become a hybrid of technical design and political processes with major impact on markets, social welfare, and economic activity. Standards increasingly develop outside government regulatory venues in consortia and other forms of voluntary consensus bodies involving collaboration among private sec...

Background. Peripheral arterial occlusive disease (PAOD) is the most common peripheral vascular disorder in the elderly. A clear picture of the disease’s course, especially in patients with non-critical limb ischaemia (Fontaine stages I and II), is essential for the general practitioner, who plays a key role in the diagnosis and management of PAOD. Aim. To evaluate the population-based evidence...

The term Klinefelter syndrome (KS) describes a group of chromosomal disorder in which there is at least one extra X chromosome to a normal male karyotype, 46,XY. XXY aneuploidy is the most common disorder of sex chromosomes in humans, with prevalence of one in 500 males. Other sex chromosomal aneuploidies have also been described, although they are much less frequent, with 48,XXYY and 48,XXXY b...

The structure and dynamics of penta-hepta defects (PHD’s) in hexagonal patterns are studied in the framework of coupled amplitude equations for the underlying plane waves. An analytical solution for the phase field of moving PHD is found in the far field, which generalizes the static solution due to Pismen and Nepomnyashchy. The mobility tensor of the PHD is calculated using a combined analytic...