545 Acta Endocrinologica (Buc), vol. X, no. 4, p. 545-558, 2014 *Correspondence to: Daniel Boda MD, PhD, “Carol Davila” University of Medicine and Pharmacy Dermatology Research Laboratory, 22-24 Gr. Manolescu, Sector 1, Bucharest, 0111234, Romania, E-mail: [email protected] Abstract Context. Melanoma is the most aggressive skin cancer, with significant morbidity and mortality, and one facto...

Endothelial cells growing in high glucose-containing medium show reduced cell proliferation and in vitro angiogenesis. Evidence suggests that the molecular pathways leading to these cellular responses are controlled by microRNAs, endogenous post-transcriptional regulators of gene expression. To identify the microRNAs and their targeted genes involved in the glucose responses, we performed the m...

A 492 GHz quasioptical superconductor-insulator-superconductor (SIS) heterodyne receiver for submillimeter astronomy has been constructed with a double-sideband noise temperature of 170+25 K, where the system response is an average over a 600 MHz i.f. bandwidth centered at 1.5 GHz. The excellent sensitivity is achieved through use of a planar twin-slot antenna feeding a pair of Nb-&OX-Nb juncti...

527 percentiles calculated. 2 Applying the BSAC formula 4 to pharmaco-kinetic data (C max of ∼3.2 mg/L following an oral dose of 250 mg with a terminal half-life of 7–8 h), an MIC susceptible breakpoint (BP) of 0.4 mg/L was calculated. MIC data were reviewed to ascertain the ABT-492 MIC ranges for the 'wild sensitive' populations. For Enterobacteriaceae, In the case of staphylococci, the MIC ra...

Teasing is ambiguous. Although the literal content of a tease is, by definition, negative, seldom do teasers intend for their tease to be taken literally. Toward this aim, teasers often attempt to mitigate the negative surface content of the tease by communicating via gesture, facial expression, or tone of voice that they are "just kidding." The research presented here suggests that such attemp...

One of the largest Q fever outbreaks ever occurred in the Netherlands from 2007-2010, with 25 fatalities among 4,026 notified cases. Airborne dispersion of Coxiella burnetii was suspected but not studied extensively at the time. We investigated temporal and spatial variation of Coxiella burnetii in ambient air at residential locations in the most affected area in the Netherlands (the South-East...

Objectives. To evaluate the sperm chromatin dispersion in men with infertility using first Russian kit. Methods. The study was conducted between July and August 2022. Study participants were 492 male volunteers aged 23 to 59 years which semen samples examined by GEMSTANDART–HaloSperm L&Q kit so-called Halo test. outcomes as a percentage DNA Fragmentation Index (DFI), %. results of test eval...