The mol-ecule of the title compound, C(5)H(4)Cl(2)N(2)O, is close to being planar (r.m.s. deviation = 0.013 Å), apart from the C atom of the meth-oxy group, which deviates by 1.082 (2) Å from the mean plane of the other atoms. In the crystal, short Cl⋯N contacts [3.0940 (15) and 3.1006 (17) Å] generate a three-dimensional framework.

The non-H atoms of the title compound, C(10)H(9)BrO(5), are essentially coplanar, with the exception of the ester group [the O=C-O-C torsion angle is -143.4 (3)°].

In the mol-ecule of the title compound, C(17)H(15)Cl(2)N(3)O, the triazole ring is oriented at dihedral angles of 9.24 (6) and 82.49 (6)°, respectively, with respect to the phenyl and dichloro-benzene rings. The dihedral angle between the dichloro-benzene and phenyl rings is 88.57 (5)°. An intra-molecular C-H⋯O contact results in the formation of a planar five-membered ring.

Opioid receptors are synthesized in dorsal root ganglia and transported into peripheral terminals of primary afferent neurons. Activation of such receptors results in antinociceptive effects that are most prominent in inflammation. In addition, opioid receptors located on sympathetic postganglionic neuron terminals may be involved in these effects. This study investigates the peripheral analges...

2-Mercapto-1-methyl-imidazoline (N(2)C(4)H(6)S) is converted at room temperature into 2-bromo-1-methyl-imidazole (N(2)C(4)H(5)Br) in presence of copper(I) bromide in acetonitrile-chloroform mixture via extrusion of sulfur as sulfate and oxidation of Cu(I) into Cu(II). 2-Bromo-1-methyl-imidazole was isolated as its self assembled tetranuclear Cu(II) cluster, [Cu(4)(η(1)-N-(N(2)C(4)H(5)Br)(4)(μ(4...

could be prepared by employing appropriate precursor molecules. Nanotubes containing both boron and nitrogen have Carbon nanotubes containing small amounts of nitrogen are been grown in the electric arc discharge between graphite produced by the pyrolysis of aza-aromatics such as pyridine, cathodes and graphite anodes filled with boron in a nitrogen methylpyrimidine and triazine over cobalt nan...

Cultured rat vascular smooth muscle cells (VSMCs) possess receptors for potent vasoconstrictor endothelin-1 (ET-1) as well as potent vasodilator natriuretic peptides (atrial, brain, and C-type natriuretic peptides [ANP, BNP, and CNP, respectively]). However, little is known about molecular interactions between endothelin receptors and natriuretic peptides in VSMCs. To elucidate whether natriure...