gem-Dibromocyclopropane 1, prepared from tri-O-benzyl-D-glucal, undergoes thermal and silver-promoted ring expansion in the presence of alcohols to give substituted oxepines. With further heating, ring contraction to highly substituted tetrahydrofurans follows. These represent C-furanosides, potentially useful as precursors to C-nucleosides and other carbohydrate mimics.

An efficient base-catalyzed synthesis of arylated pyridines has been disclosed. This reaction involving conjugated acetylenes and substituted benzylamines proceeded smoothly, giving rise to tri-aryl substituted pyridines which are biologically relevant compounds in good to excellent yields in N,N-dimethylformamide (DMF) under air at 140 °C with K₂CO₃ as catalyst.

Different reactions of Mes* substituted phosphanes (Mes* = 2,4,6-tri-tert-butylphenyl) led to the formation of the bicyclic tetraphosphane Mes*P4Mes* (5) and its unknown Lewis acid adduct 5·GaCl3. In this context, the endo-exo isomer of 5 was fully characterized for the first time. The synthesis was achieved by reactions involving "self-assembly" of the P4 scaffold from P1 building blocks (i.e....

Crystals of bis-(tetra-butyl-ammonium) di-μ3-chlorido--tris-(μ2-4-iodo-pyrazolato-κ2N:N')tris-[chlorido-cuprate(II)] 1,4-dioxane hemisolvate, (C16H36N)2[Cu3(C3H2IN2)3Cl5]·0.5C4H8O or (Bu4N)2[CuII3(μ3-Cl)2(μ-4-I-pz)3Cl3]·0.5C4H8O, were obtained by evaporating a solution of (Bu4N)2[{CuII(μ-OH)(μ-4-I-pz)} n CO3] (n = 27-31) nanojars in chloro-form/1,4-dioxane. The decomposition of chloro-form in t...

interest in agrochemicals and drugs. Aryl group substituted pyrazoles and imidazoles, in particular, have been studied because their biological activities are strongly dependent on their substituents on the pyrazole ring system. 1,5-Diaryl substituted pyrazole (SR141716A, 1), which has a hydrazide group on the 3-position of the pyrazole ring, has recently been synthesized and identified as the ...

[reaction: see text] Synthesis of glycosyl cyanides was optimized with a new catalyst system. Reduction of tri-O-acetyl-beta-L-fucopyranosyl cyanide with Pd-hydrogen, in the presence of Ac(2)O and Boc(2)O, gave N-protected-mono- and -di-(2,3,4-tri-O-acetyl-beta-L-fucopyranosylmethyl)-amines, which allow for the syntheses of small cluster oligosaccharide mimetics of fucopyranosylomethyl-substitu...

New 6-CF3-1H-pyrazolo[3,4-b]quinolines with a methyl and/or phenyl group attached to the pyrazole core (Molx (x = 1, 2, 3, 4)) were synthesized and characterized in terms of their optoelectronic applications: photovoltaic electroluminescence. The fluorescence emissions investigated phenyl-decorated pyrazoloquinolines is caused by photoinduced charge transfer p process occurring between substitu...