Adenovirus (Ad) precursor terminal protein (pTP) in a complex with Ad DNA polymerase (pol) serves as a primer for Ad DNA replication. During initiation, pol covalently couples the first dCTP with Ser-580 of pTP. By using an in vitro reconstituted replication system comprised of purified proteins, we demonstrate that the conserved Asp-578 and Asp-582 residues of pTP, located close to Ser-580, ar...

The discovery of high-frequency brightness oscillations in thermonuclear X-ray bursts from several neutron star low-mass X-ray binaries has important implications for the beat frequency model of kilohertz quasi-periodic brightness oscillations, the propagation of nuclear burning, the structure of the subsurface magnetic fields in neutron stars, and the equation of state of high-density matter. ...

OBJECTIVES The incidence of non-alcoholic fatty liver disease (NAFLD) is significant in hepatitis C virus (HCV) carriers due to multiple mechanisms, and this worsens the progression of chronic liver diseases, such as cirrhosis and hepatocellular carcinoma, and death. The purpose of this study was to examine whether the alanine aminotransferase/aspartate aminotransferase (ALT/AST) ratio correlat...

in this paper, it was shown that , where  and , and , where  is not prime and , are od-characterizable.

let $g$ be a connected graph with vertex set $v(g)$‎. ‎the‎ ‎degree resistance distance of $g$ is defined as $d_r(g) = sum_{{u‎,‎v} subseteq v(g)} [d(u)+d(v)] r(u,v)$‎, ‎where $d(u)$ is the degree‎ ‎of vertex $u$‎, ‎and $r(u,v)$ denotes the resistance distance between‎ ‎$u$ and $v$‎. ‎in this paper‎, ‎we characterize $n$-vertex unicyclic‎ ‎graphs having minimum and second minimum degree resista...

Specimen 1 Organisms Referees Frequency Ext 1 Ext 2 571 Ascaris lumbricoides 18 Moderate to Many 15 49 545 Entamoeba coli 10 Moderate to Many 4 16 589 Schistosoma mansoni 6 Few to moderate 3 11 524 Parasite(s) found referred for ID 10 580 Trichuris trichiura 3 Few to moderate 6 544 Endolimax nana 2 2 574 Hookworm 1 546 Entamoeba hartmanni 1 548 Entamoeba histolytica / Entamoeba dispar 1 566 Hym...

In this note I amend and clarify the framework for cost analysis developed and applied by Morrison and Schwartz (M&S) in a series of papers. I propose a consistent decomposition of a cost-based measure of short-run returns to scale and develop a version of M&S's dynamic decomposition that makes transparent its nature and usefulness as a cost-accounting device. __________________________________...

The substantial merit of Cordyceps s.l. spp. in terms of medicinal benefits is largely appreciated. Nevertheless, only few studies have characterized and examined the clinical complications of the use of health tonics containing these species. Here, we epitypified C. formosana isolates that were collected and characterized as Ophiocordyceps formosana based on morphological characteristics, mole...

Introduction ................................................ 573 I. Wade's Seven Factors for Assessing Product Defects ... 578 A. W ade's Analysis ................................... 580 B. Reorganization of the Factors ...................... 580 C. Assessment of the First Six Factors ................ 581 D. The Producer as Insurer .......................... 584 II. Alternative Risk-Utility Me...