introduction: this study was launched to evaluate the sensitivity and specificity of 99mtc-ciprofloxacin to distinguish infection foci induced by staphylococcus aureus and inflammation lesions induced by carrageenan in the rat foot in comparison with 67ga-citrate scintigraphy. methods: the labeling and quality control of 99mtc-ciprofloxacin kits have been performed according to the manufacture...

introduction: bombesin is a 14-aminoacid peptide isolated from frog skin. the mammalian counterparts of the frog peptide are neuromedin b (nmb) and gastrin-releasing peptide (grp). bombesin (bbn) is a peptide showing high affinity for the gastrin releasing peptide receptor (grpr). prostate, small cell lung cancer, breast, gastric, and colon cancers are known to over express receptors to bombesi...

   Various radiometal complexes have been developed for tumor imaging, especially Ga-68 tracer. In the present study, the development of a radiogallium bis-thiosemicarbazone complex has been reported. [67Ga] acetylacetonate bis(thiosemicarbazone) complex ([67Ga] AATS) was prepared starting [67Ga]Gallium acetate and freshly prepared acetylacetonate bis (thiosemicarbazone) (AATS) in 30 min at 90°...

   Various radiometal complexes have been developed for tumor imaging, especially Ga-68 tracer. In the present study, the development of a radiogallium bis-thiosemicarbazone complex has been reported. [67Ga] acetylacetonate bis(thiosemicarbazone) complex ([67Ga] AATS) was prepared starting [67Ga]Gallium acetate and freshly prepared acetylacetonate bis (thiosemicarbazone) (AATS) in 30 min at 90°...

PURPOSE To evaluate the long-term action of deflazacort (DF), a new calcium-sparing and bone-saving corticosteroid, in chronic sarcoidosis patients needing prolonged therapy. PATIENTS AND METHODS 40 patients with chronic histologically proved sarcoidosis requiring long-term corticosteroid therapy were treated with DF and followed for a mean period of 958 +/- 515 days (range 382-2, 068). The i...

breast cancer radioimmunoscintigraphy targeting her2/neu expression is a growing fieldof work in nuclear medicine research. in this study, trastuzumab was successively labeledwith [67ga] gacl3 after conjugation with dota-nhs-ester.the conjugates were purified by molecular filtration, the average number ofdota conjugated per mab was calculated and total concentration was determined byspectrophot...

We thank Professor Sharma for his interest in our work, and for his comments. Our study was retrospective, from October 1978 in Milan, and from October 1980 in Padua. In the early 1980s, our patients underwent 67Ga lung scan, whilst 67Ga total body scan was introduced in 1986. For this reason, we could not show the 67Ga total body scan in the work-up of our patients over so many years of follow...