Treatment of 7-chloro-1-phenylpyrimido[4,5-e][1,3,4]thiadiazines with hydrazine in boiling ethanol gave corresponding7-hydrazinyl derivatives. Diazotization of the latter compounds acheived a mixture of 5H-tetrazolo[1',5':1,2]pyrimido[4,5-e][1,3,4]thiadiazine and 9H-tetrazolo[5',1':2,3]pyrimido[4,5-e][1,3,4]thiadiazines. Ratio of these two group of products determined by 1HNMR studies and no si...

A series of 7-substituted-3-(4-(3-(4-substitutedphenyl)-4,5-dihydroisoxazol-5-yl)phenyl)-2-substituted quinazolin-4(3H)-one (1-30) have been synthesized by the cyclization of (E)-3-(4-(3-substitutedphenyl)acrylolyl)phenyl)-2-(substitutedphenyl)-7-substituted quinazolin-4-(3H)-one with hydroxylamine hydrochloride. The synthesized compounds were examined for their in vivo antihypertensive activit...

Basic studies on concentrated solutions are becoming more and important due to the practical industrial geological applications. The use in redox flow batteries is one of most applications these solutions. Specifically, this paper we investigated high-concentrated copper chloro-complexes with different additives. concentration ligands additives affects physicochemical electrochemical properties...

The unit cell of the title compound, C(13)H(9)Cl(2)NO(3)S·0.5C(7)H(8), contains two mol-ecules of 2-chloro-N-(4-chloro-benzo-yl)benzene-sulfonamide and one toluene mol-ecule, which is disordered about a centre of inversion. The dihedral angle between the two aromatic rings is 85.7 (1)°. In the crystal, mol-ecules are linked by pairs of N-H⋯O(S) hydrogen bonds, forming centrosymmetric dimers.

In the title thio-ether dihydrate, C(18)H(10)Cl(2)N(2)S·2H(2)O, the S-bound quinolinyl residues are almost orthogonal, forming a dihedral angle of 72.36 (4)°. In the crystal, the four water mol-ecules are connected via an eight-membered {⋯OH}(4) synthon with each of the four pendent water H atoms hydrogen bonded to a pyridine N atom to stabilize a three-dimensional architecture.

In continuing studies of drugs against Mycobacterium leprae in mice we have tested the following compounds: lincomycin, clinimycin (7( S ) -chloro-7 -deoxylincomycin, clindamycin) , U-24729A (4' -pentylN -demethyl-7 -chlorolincomycin), amicetin, phosphonomycin, ABT-29666 (1-{3-[ 4-(pchlorophenyl-azo )-5, 6, 7, 8-tetrahydro-1naphthylamino] propyl} piperidine), ABT38396 (1{3-[ 4-( 6-methoxy-3-pyr...