Abstract Glioblastoma are incurable primary tumors of the central nervous system. Novel treatment options urgently needed. Recently, we investigated molecular effects disrupting (b)HLH network, a frequently altered and tumor-promoting transcriptional network in glioma, by introducing dominant-negative variant E47 protein. The identified downstream anti-tumor included DNA damage response pathway...

This paper aims to determine whether coronavirus (COVID-19) causes cost increases in accommodation enterprises and, if any, what these costs are. Additionally, executive perspectives were taken on operational budgets for 2020, occupancy rates, profitability, the decision stay or off, and expectations following year. The case study employed a qualitative research method, multiple caseholistic de...