T cell receptor (TCR) signaling involves CD4/CD8-p56lck recruitment of ZAP-70 to the TCR receptor, ZAP-70 phosphorylation of LAT that is followed by LAT recruitment of the GADS-SLP-76 complex. Back regulation of ZAP-70 by SLP-76 has not been documented. In this paper, we show that anti-CD3 induced ZAP-70 cluster formation is significantly reduced in the absence of SLP-76 (i.e., J14 cells) and i...

The properties of the excited states of 76Kr, populated in the decay of 76Rb produced at ISOLDE isotopic separator, have been investigated by using K-conversion electron, γ -ray, and γ -γ coincidence measurements. The lifetimes of several levels have been measured by means of the advanced time-delayed βγ γ (t) method. The identification of 19 new levels and 55 transitions and the information de...

introduction: deep neck space infections (dnsi) are serious diseases that involve several spaces in the neck. the common primary sources of dnsi are dental infections, tonsillar and salivary gland infections, malignancies, and foreign bodies. with widespread use of antibiotics, the prevalence of dnsi has been reduced. common complications of dnsi include airway obstruction, jugular vein thrombo...