OBJECTIVE: Community health centers (HCs) provide care for millions of medically underserved Americans with disproportionate burdens of hypertension and hyperlipidemia. For both conditions, treatment guidelines recently became more stringent and quality improvement (QI) efforts have intensified. We assessed hypertension and hyperlipidemia management in HCs during this time of guideline revision...

This randomized, parallel-group study in patients inadequately controlled on olmesartan medoxomil/amlodipine (OLM/AML) 40/10 mg assessed the effects of adding hydrochlorothiazide (HCTZ) 12.5 mg and 25 mg, using seated blood pressure (SeBP) measurements and ambulatory blood pressure (BP) monitoring. Enrolled patients were screened and tapered off of therapy if required. All patients received OLM...

The enzyme 11hydroxysteroid dehydrogenase type 2 plays a major role in blood pressure regulation. It metabolizes glucocorticoid hormones into derivatives with low affinity for the mineralocorticoid receptor, preventing its permanent occupancy by circulating cortisol, which is 100to 1000-fold more abundant than aldosterone in the plasma. Inactivating mutations of the enzyme result in severe hype...

BACKGROUND To compare the prescription modalities of general practitioners (GPs) and rheumatologists (RHs) for symptomatic knee osteoarthritis (OA) and to determine correlates with prescription of low-dose NSAIDs. METHODS This observational, prospective, national survey was carried out among a national representative sample of GPs (n = 808) and RHs (n = 134). Each physician completed a medica...

We present interferometric observations of the SiO J = 2-1, H 13CO+ J = 1-0, HC 3N J = 11-10, CH 30H JK = 2o-1o, and so2 JKpKo = 817-808 transitions along with the A= 3.1 mm continuum toward the young stellar object Orion S. The HC3N and H 13CO+ emission trace similar spatial and velocity distributions which are extended and follow the Orion molecular ridge. The SiO emission is more spatially c...

Identifying the main byproducts of SF6 decomposition proves to be an effective strategy for determining nature and severity internal discharge faults in gas-insulated switchgears (GISs). In this research, it was suggested utilize coordination polymer Zr-MOF-808 as a sensor decomposition. This study examined adsorption its products (CF4, CS2, SO2, SO2F2, SOF2) on Zr-MOF-808, utilizing Gaussian16...

CONTEXT The clinical use of ambulatory blood pressure (BP) monitoring requires further validation in prospective outcome studies. OBJECTIVE To compare the prognostic significance of conventional and ambulatory BP measurement in older patients with isolated systolic hypertension. DESIGN Substudy to the double-blind placebo-controlled Systolic Hypertension in Europe (Syst-Eur) Trial, started ...

A green route to prepare Zr-based MOF-808 with controlled crystal size have been developed. is able decontaminate wastewater by simultaneously degrading a toxic pesticide and recovering phosphate ions.