OBJECTIVE To establish the extent to which systematic reviews and meta-analyses of individual participant data (IPD) are being used to inform the recommendations included in published clinical guidelines. DESIGN Descriptive study. SETTING Database maintained by the Cochrane IPD Meta-analysis Methods Group, supplemented by records of published IPD meta-analyses held in a separate database. ...

background praziquantel, an antischistosomal compound, is used as first-line drug for chemotherapy of schistosoma japonicum since 1984. in this article, we conducted a systematic review and mete-analysis to evaluate the efficacy and safety of different dosages of praziquantel (pzq) for treatment of schistosoma japonicum. evidence acquisition: a number of six articles published in peer-reviewed ...

OBJECTIVE Psychotherapy research may suffer from factors such as a researcher's own therapy allegiance. The aim of this study was to evaluate if researcher allegiance (RA) was reported in meta-analyses and randomised controlled trials (RCTs) of psychotherapeutic treatments. DESIGN Systematic approach using meta-analyses of different types of psychotherapies. DATA SOURCES Medline, PsycINFO a...

The open source project Edutella is an RDF-based Peer-to-Peer infrastructure for digital resources, focusing on learning materials. Building upon the established meta-data standard RDF(S) appropriate for the description of distributed resources in the World Wide Web WWW, it provides a general RDF-based metadata infrastructure for P2P applications. In this paper, after a short introduction to th...

Background: Pre-eclampsia (PE) is a pregnancy disorder characterized by hypertension and proteinuria. The evidence has suggested that microRNAs (miRs) are associated with pre-eclampsia pathogenesis; however, these results are inconsistent. The aim of this study was to assess the association between miR-210 expression and PE risk. Methods: Previous studies were selected using PubMed, Scopus, ...