Sesame (Sesamum indicum L.) seed and oil have long been used widely as healthy foods to supply energy and prevent aging. Some of the main active anti-oxidative constituents in sesame seeds are γ-tocopherol and phenols. The purpose of this study was to investigate the relationship between roasting temperature and time with γ-tocopherol and total phenolic compounds (TPC) of sesame seeds when roas...

Phytyl diphosphate (PDP) is the prenyl precursor for tocopherol biosynthesis. Based on recent genetic evidence, PDP is supplied to the tocopherol biosynthetic pathway primarily by chlorophyll degradation and sequential phytol phosphorylation. Three enzymes of Arabidopsis (Arabidopsis thaliana) are known to be capable of removing the phytol chain from chlorophyll in vitro: chlorophyllase1 (CLH1)...

Rapeseed (Brassica napus L.) is the most important oil crop of temperate climates. Rapeseed oil contains tocopherols, also known as vitamin E, which is an indispensable nutrient for humans and animals due to its antioxidant and radical scavenging abilities. Moreover, tocopherols are also important for the oxidative stability of vegetable oils. Therefore, seed oil with increased tocopherol conte...

Although the role of tocopherol in the nutrition of small laboratory animals has been extensively investigated, relatively little attention has been given to the requirement of larger domestic animals. Evidence is conflicting about any function or effect tocopherol may have on pig nutrition. Bratzler, Loosli, Krukovsky & Maynard (1950) found that tocopherol supplementation of a diet low in toco...

The effect of -tocopherol treatment on gene expression in human aortic vascular smooth muscle cells was analyzed by gene expression arrays. The expression of the connective tissue growth factor (CTGF) gene was induced by -tocopherol 1.8-fold in gene array experiments, and similar results were also obtained by RT-PCR (1.7-fold) and at the protein level (1.4-fold). The antioxidants -tocopherol an...

INTRODUCTION: Strenuous exercise in sedentary individuals increases the acute risk of atherothrombotic events and depletes endogenous antioxidants. Supplementation with the antioxidant tocopherol ameliorates the risk; however it is unclear whether α-tocopherol, γ-tocopherol or a combination of both is more efficacious. We therefore measured the effects of γ-,αand mixed tocopherol supplementatio...

INTRODUCTION: Strenuous exercise in sedentary individuals increases the acute risk of atherothrombotic events and depletes endogenous antioxidants. Supplementation with the antioxidant tocopherol ameliorates the risk; however it is unclear whether α-tocopherol, γ-tocopherol or a combination of both is more efficacious. We therefore measured the effects of γ-,αand mixed tocopherol supplementatio...

BACKGROUND Tocopherols are important antioxidants in vegetable oils; when present as vitamin E, tocopherols are an essential nutrient for humans and livestock. Rapeseed (Brassica napus L, AACC, 2 n = 38) is one of the most important oil crops and a major source of tocopherols. Although the tocopherol biosynthetic pathway has been well elucidated in the model photosynthetic organisms Arabidopsis...

The effects of coenzyme Q(10) (CoQ(10)) and alpha-tocopherol on the rate of mitochondrial superoxide anion radical (O2(./-)) generation were examined in skeletal muscle, liver, and kidney of 24-month-old mice. Mice were orally administered alpha-tocopherol (200 mg.kg(-1).day(-1)) alone, CoQ(10) (123 mg.kg(-1).day(-1)) alone, or the two together for 13 wk. Administration of alpha-tocopherol resu...

Tocopherols are lipophilic antioxidants that are synthesized exclusively in photosynthetic organisms. In most higher plants, aand g-tocopherol are predominant with their ratio being under spatial and temporal control. While a-tocopherol accumulates predominantly in photosynthetic tissue, seeds are rich in g-tocopherol. To date, little is known about the specific roles of aand g-tocopherol in di...