نتایج جستجو برای: abdominal aortic aneurysms

تعداد نتایج: 203858  

2011
Ellen S. Regalado Dong-chuan Guo Carlos Villamizar Nili Avidan Dawna Gilchrist Barbara McGillivray Lorne Clarke Francois Bernier Regie L. Santos-Cortez Suzanne M. Leal Aida M. Bertoli-Avella Jay Shendure Mark J. Rieder Deborah A. Nickerson Dianna M. Milewicz

Rationale: Thoracic aortic aneurysms leading to acute aortic dissections (TAAD) can be inherited in families in an autosomal dominant manner. As part of the spectrum of clinical heterogeneity of familial TAAD, we recently described families with multiple members that had TAAD and intracranial aneurysms or TAAD and intracranial and abdominal aortic aneurysms inherited in an autosomal dominant ma...

Journal: :European Journal of Vascular and Endovascular Surgery 2018

Journal: :The Journal of clinical investigation 2012
Dianna M Milewicz

Aortic aneurysms are a common clinical condition that can cause death due to aortic dissection or rupture. The association between aortic aneurysm pathogenesis and altered TGF-β signaling has been the subject of numerous investigations. Recently, a TGF-β-responsive microRNA (miR), miR-29, has been identified to play a role in cellular phenotypic modulation during aortic development and aging. I...

2015
Eun-Ki Min Young Hoon Kim Duck Jong Han Youngjin Han Hyunwook Kwon Byung Hyun Choi Hojong Park Ji Yoon Choi Tae-Won Kwon Yong-Pil Cho

Although the standard treatment of abdominal aortic aneurysm has shifted from open surgery to endovascular repair, open surgery has remained the standard of care for complex aneurysms involving the visceral arteries and in patients unsuitable for endovascular aneurysm repair. Postoperative renal insufficiency may occur after open surgical repair of suprarenal abdominal aortic aneurysm. Methods ...

Journal: :European Journal of Vascular and Endovascular Surgery 2003

Journal: :American Journal of Roentgenology 1989

Journal: :iranian journal of medical sciences 0
ramachandran meenakshisundaram department of institute of internal medicine, madras medical college, chennai. chennai, india. dipti agarwal ponniah thirumalaikolundusubramanian

dear editor, abdominal aortic aneurysm is often asymptomatic, less recognized, and causes considerable mortality and morbidity, if missed. the incidence varies from country to country and the occurrence is influenced by modifiable (smoking, coronary heart disease, hypertension, dyslipidemia, and prolonged steroid therapy) and non-modifiable risk factors (increasing age, male gender, and positiv...

Journal: :European Journal of Vascular and Endovascular Surgery 2014

Journal: :Circulation research 2015
Nasim Nosoudi Pranjal Nahar-Gohad Aditi Sinha Aniqa Chowdhury Patrick Gerard Christopher G Carsten Bruce H Gray Naren R Vyavahare

RATIONALE Matrix metalloproteinases (MMPs)-mediated extracellular matrix destruction is the major cause of development and progression of abdominal aortic aneurysms. Systemic treatments of MMP inhibitors have shown effectiveness in animal models, but it did not translate to clinical success either because of low doses used or systemic side effects of MMP inhibitors. We propose a targeted nanopa...

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