INTRODUCTION Symptoms of ovarian cancer are often vague and consequently a high proportion of women with ovarian cancer are not referred to the appropriate clinic. OBJECTIVE To identify diagnostic factors for ovarian cancer. DESIGN A qualitative and quantitative study. SETTING Four UK hospitals. SAMPLE One hundred and twenty-four women referred to hospital with suspected ovarian maligna...

Liposarcoma is the most common malignant soft tissue tumor in adults. Extremities and retroperitoneum are sites of involvement liposarcoma. gastrointestinal tract rare colon an extremely uncommon site. Mesenchymal tumors bowel mainly represented by stromal (GIST). A sixty-one-year-old male patient presented with abdominal pain distension. Contrast-enhanced computerized tomography (CECT) showed ...

Context: Pathologic aerophagia is defined as air swallowing causing abdominal distension and/or repetitive flatulence/belching present for greater than 12 weeks in a year. Pathologic aerophagia, which can be exacerbated by anxious behavior, is common in Rett Syndrome patients and can cause significant distress. Case report: We report a case of an 8-year-old female, with Rett Syndrome, who devel...

Aerophagia is a functional gastrointestinal disorder characterized by repetitive air swallowing, abdominal distension, belching and flatulence. Pathologic aerophagia is a condition caused by the swallowing of excessive volumes of air with associated various gastrointestinal symptoms, such as burping, abdominal cramps, flatulence and a reduced appetite. It is a clinical entity that can simulate ...

BACKGROUND Gut content may be determinant in the generation of digestive symptoms, particularly in patients with impaired gut function and hypersensitivity. Since the relation of intraluminal gas to symptoms is only partial, we hypothesized that non-gaseous component may play a decisive role. METHODS Abdominal computed tomography scans were evaluated in healthy subjects during fasting and aft...

Background: Patients with functional gut disorders manifest poor tolerance to intestinal gas loads but the mechanism of this dysfunction is unknown. Aim: Our aims were firstly, to explore the relative importance of the amount of intestinal gas versus its distribution on symptom production, and secondly, to correlate gut motility and perception of gas loads. Subjects: Fourteen healthy subjects w...

Vulvar leiomyomas are extremely rare smooth muscle tumors that easily mistaken for other lesions, as the differential diagnosis must consider a wide spectrum of benign and malignant lesions. We present case 52-year-old woman with three-year history progressive abdominal distension pain an enlarging vulvar mass distorting labia majora causing gait disturbance. Imaging confirmed enormous pelvic o...