OBJECTIVE To investigate the ovarian activity before and after gonadal suppression with GnRH-analog in patients with PCO, hyperandrogenism, hyperinsulinism and acanthosis nigricans. DESIGN Controlled clinical study. SETTING Tertiary academic medical center. PATIENTS Six patients with clinical findings of PCO, hirsutism and acanthosis nigricans. INTERVENTIONS Morning blood samples in the...

Acne vulgaris is a common skin condition which can present as a part of metabolic syndrome called polycystic ovarian syndrome(PCOS). This study was done to determine the associated cutaneous findings in acne, its association with PCOS and the hormonal changes in acne vulgaris. A prospective study was done on 50 female patients who presented with acne. Presence of associated clinical manifestati...

BACKGROUND Acanthosis nigricans (AN) develops sporadically or in association with obesity, insulin-resistance and dark pigmentary phenotype. Unusual clinical presentations of AN may be diagnostically vexing. OBJECTIVES The aim of the report is to present unusual clinical and dermoscopic pictures of hyper-keratotic, brownish lesions of the nipples resembling acanthosis nigricans. PATIENTS/ME...

BACKGROUND The purpose of this study was to determine the prevalence of high blood pressure (HBP) and associated risk factors in school children 8 to 13 years of age. METHODS Elementary school children (n = 1,066) were examined. Associations between HBP, body mass index (BMI), gender, ethnicity, and acanthosis nigricans (AN) were investigated using a school based cross-sectional study. Blood ...

The skin is a unique marker for malignancy as these cutaneous manifestation not only often precede the development of other symptoms, but also often cause patients to seek medical attention sooner than they would for other symptoms. Common cutaneous markers for malignancy include: acanthosis nigricans, carcinoid syndrome, Leser-Trelat sign, and necrolytic migratory erythema. Although these skin...

background: acanthosis nigricans (an) is a brown to black, velvety hyperpigmentation of the skin that usually involves cutaneous folds. treatment of an is important regarding cosmetic reasons and various therapeutic modalities have been used for these purposes. the goal of this study was to compare the effectiveness of long-pulsed alexandrite laser and topical tretinoin-ammonium lactate for tre...