BACKGROUND Specific immunotherapy could be a therapeutic tool for the increasing problem of sensitisation to Natural Rubber Latex (NRL). OBJECTIVE To investigate the tolerability of SLIT for Latex and its effects on skin reactivity. METHODS Twenty-six patients (mean age 35.5 years) with an average history of 7.5 years of cutaneous symptoms plus respiratory symptoms (23/26) due to NRL were s...

RUSH/SMARCA3 (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A, member 3) is capable of sequence-selective DNA binding and ATP-dependent DNA unwinding. In rabbit uterine epithelial cells, RUSH-1alpha (113 kDa) is the progesterone-dependent splice variant and RUSH-1beta (95 kDa) is the oestrogen-dependent splice variant. Rabbit RUSH/SMARCA3 mRNA is primarily r...

Methods From June 2008 to June 2012, the severity of SR was assessed at double-blind placebo-controlled food challenge test (DBPCFC) to evaluate if they were candidates for rush oral immunotherapy or not. The medical records of 342 patients who showed positive reaction at DBPCFC were analyzed. A hundred and forty-one were allergic to hen’s egg, 156 to milk and 45 to wheat. We modified the gradi...

Andrew N. Garman, Psy.D., associate professor and director of master’s programs, Department of Health Systems Management, Rush University, Chicago; Teresa Burkhart, senior director, Rush Health Associates, and assistant professor, Department of Health Systems Management, Rush University; and Jeremy Strong, administrator, Surgical Services, and instructor, Department of Health Systems Management...

Steroids regulate alternative splicing of RUSH/SMARCA3. The full-length, progesterone-dependent α isoform and the 3′-truncated, estrogen-dependent β isoform have identical DBDs, NLSs and RING fingers. Transcription of RUSH/SMARCA3 is mediated by a bipartite progesterone receptor halfsite/overlapping Y-box combination (-38/-26), where progesterone activation is attenuated by NF-Y binding. Regula...