Guillain-Barre syndrome (GBS)-associated achalasia is a very rare disease of uncertain cause. We report the case of a patient diagnosed with GBS-associated type I achalasia who was successfully treated with peroral endoscopic myotomy (POEM). A 30-year-old man who was diagnosed with GBS 3 mo before was referred to our department with dysphagia and meal-related regurgitation. The results of esoph...

It is the severe form of achalasia that is characterised by massive dilatation and tortuosity of the oesophagus. It is seen in long standing achalasia where the dilated upper segment of the oesophagus sags down below the level of the narrowed lower segment causing mechanical obstruction. Whereas Heller’s cardiomyotomy is considered to be the operation of choice in simple achalasia, it is regard...

Allgrove (Triple A) syndrome is a rare autosomal recessive disorder characterized by cardinal features of adrenal insufficiency due to adrenocorticotropic hormone (ACTH) resistance, achalasia, and alacrimia. It is frequently associated with neurological manifestations like polyneuropathy. Since its first description by Allgrove in 1978, approximately 100 cases have been reported in the literatu...

Submucosal dissection of the oesophagus is a rare oesophageal disorder. We report a patient who had recurrent episodes of dissection and achalasia. Both recurrence and the association with achalasia are to our knowledge unique.

Achalasia, a benign motility disorder of the esophagus, results in incomplete relaxation lower esophageal sphincter (LES) and absent peristalsis. Patients experience dysphagia, regurgitation, chest pain, weight loss, heartburn. Pharmacological therapy has been unsatisfactory definitive treatment focused on mechanical disruption tight LES. Peroral endoscopic myotomy (POEM) is safe minimally inva...

achalasia is a well- defined esophageal motor disorder. graded pneumatic dilation using rigiflex ballon is one of the therapeutic modalities that had not been evaluated in a large long-term study. we aimed at evaluating long-term efficacy of graded rigiflex pneumatic dilation in the treatment of achalasia. symptomatic patients with achalasia who had been referred to our center were consecutivel...

138 " Chicago Classification " Should Be Challenged in the Diagnosis of Achalasia: Heterogeneity of Achalasia Figure 1. Clinical findings of a 12-year-old female with solid dysphagia. (A) Upper endoscopy shows dilated esophagus and retained food material. (B) Lower esophageal sphincter is not opened with air inflation. (C) Esophageal dilata-tion with bird-beak narrowing of the esophagogastric j...

Objective: Achalasia is a disease characterized by lower esophageal sphincter motility disorder. Whereas there no clear algorithm in treating achalasia children, Heller myotomy known to be as the most effective method. Gastroesophageal reflux after frequently reported complication. Therefore, fundoplication procedure should added simultaneously. Our study aimed present results of patients who u...

IMPORTANCE Although successful treatment of achalasia depends on alleviating the obstruction at the esophagogastric junction, the postintervention contractile and pressurization pattern may also play a role in outcome. OBJECTIVE To determine whether myotomy that alleviates the esophagogastric junction outflow obstruction in achalasia might improve peristalsis. DESIGN Retrospective study fro...

Achalasia cardia is one of the common causes of motor dysphagia. Though the disease was first described more than 300 years ago, exact pathogenesis of this condition still remains enigmatic. Pathophysiologically, achalasia cardia is caused by loss of inhibitory ganglion in the myenteric plexus of the esophagus. In the initial stage, degeneration of inhibitory nerves in the esophagus results in ...