Regulatory approval of topical nadifloxacin for the treatment of acne vulgaris was based on data from controlled and randomised clinical trials using a monotherapy regimen. Frequently in dermatological practice, however, multi-regimen approaches are used. This prospective trial was conducted to assess clinical use and value of topical nadifloxacin in the treatment of acne vulgaris under routine...

BACKGROUND Acne vulgaris is a distressing condition that affects the majority of adolescents, but the impact of acne vulgaris on the psychological aspects in this age group is poorly understood. OBJECTIVE The purpose of this study was to determine the prevalence of acne, and the level of emotional, social, and functional impairments among Korean adolescents with acne. METHODS Five hundred f...

Acne vulgaris is a common inflammatory skin condition. Although often perceived as a self limited disease of adolescence, its prevalence remains high into adulthood. Nearly 90% of teenagers have acne, and half of them continue to experience symptoms as adults. By age 40 years, 1% of men and 5% of women still have lesions. Recent analyses show an increasing prevalence of acne in children, perhap...

INTRODUCTION Acne vulgaris affects over 80% of teenagers, and persists beyond the age of 25 years in 3% of men and 12% of women. Typical lesions of acne include comedones, inflammatory papules, and pustules. Nodules and cysts occur in more severe acne and can cause scarring and psychological distress. METHODS AND OUTCOMES We conducted a systematic review and aimed to answer the following clin...

Psoriasis, acne vulgaris and photoaging are common conditions. Tazarotene is a pro-drug of tazarotenic acid, a receptor-selective retinoid, which has shown efficacy in the treatment of these disorders. In the treatment of acne vulgaris, it has greater comedolytic activity than the currently available topical retinoids. In psoriasis, tazarotene normalizes keratinocyte differentiation, reverses k...

Many therapies exist in the arsenal of drugs available to dermatologists for the treatment of acne vulgaris. Among them, hormonal therapy stands out as a unique and highly efficacious treatment modality. Although some dermatologists may be hesitant to prescribe hormonal therapies, they can be safely and appropriately used in eligible female patients to treat acne vulgaris. Herein, current issue...

Background: Acne vulgaris is a dermatologic disorder with a wide variety of distribution and presentation. Its high prevalence and important cosmetic and psychological concerns focusing on contributing factors would be of great value for better approach and prevention of acne vulgaris. There are many articles that argue the role of some dietary and inflammatory factors in acne<...

the multiple etiologic factors involved in acne make the use of various medications necessary to treat the condition. this study aimed to determine the efficacy of mupirocin and rifampin used with standard treatment in the management of acne vulgaris. in a multicentre, randomized controlled, triple-blinded study, a total of 105 acne patients, with a clinical diagnosis of moderate to severe acne...

interleukin-8 (il-8) is a well-known inflammatory chemokine and suggested to be involved in the development of acne vulgaris. this study investigates il-8 plasma levels in acne patients and healthy controls and the molecular basis for the regulation of the il-8 gene in a pakistani population.patients with acne vulgaris (n=264) and healthy individuals (n=264) were enrolled in this investigation....