PURPOSE KIT aberrations were described in acral and mucosal melanomas in largely Caucasian populations. Asian populations are more prone to develop acral and mucosal than cutaneous melanomas, and may harbor a high frequency of KIT aberrations. EXPERIMENTAL DESIGN Melanoma subtypes (n = 502) were analyzed histologically to determine melanoma subtype. Tissue samples were analyzed for mutations ...

El melanoma es el cáncer de piel con mayor mortalidad a nivel mundial. Se han descrito 4 subtipos principales en cutáneo; extensión superficial, nodular, lentigo maligno y lentiginoso acral. Existen diferencias raciales la distribución frecuencia éstos subtipos. En caucásicos, riesgo para melanomas expuesta radiación UV, ya sea forma crónica o intermitente. contraste, asiáticos, afroaméricanos ...

The majority of melanocytic nevi on the soles may show 3 major dermoscopic patterns depending on the anatomical site on the sole [6] : the parallel furrow, the lattice-like, and the fibrillar patterns. Regular or irregular patterns should be identified in the fibrillar pattern. The regular fibrillar pattern is seen in acral volar melanocytic nevus, whereas the irregular fibrillar pattern is oft...

Plantar melanoma Superficial spreading melanoma Spitz nevus Dr. Taizo Kato, Department of Dermatology, Tohoku University School of Medicine, 1-1 Seiryomachi, Aobaku, Sendai 98077 (Japan) The acral regions of the limbs are the commonest site for melanoma in the Japanese [1, 2]. This high proportion of acral melanoma may be the result of the relatively low occurrence of melanoma in other parts of...

Dermatologists are often referred urgent cases of acral hematoma by general practitioners and sports medicine specialists for the purpose of excluding warts, nevi or melanoma. Acral hematoma is often a cause of anxiety to patients and their families. Here, we report a case of purpura traumatica pedis, referred to us as suspected plantar melanoma because of the finding of parallel-ridge pattern ...

We present a rare case of a patient with multiple primary acral lentiginous melanomas of the foot. We would like to highlight the importance of whole-skin examination in all patients, even by the general practitioners, aiming the maximal early detection of acral lentiginous melanomas, considering their rapid progression, early metastatic spread and extremely poor prognosis. It can be extrapolat...