A tyrosine kinase adaptor protein containing pleckstrin homology and SH2 domains (APS) is rapidly and strongly tyrosine phosphorylated by insulin receptor kinase upon insulin stimulation. The function of APS in insulin signaling has heretofore remained unknown. APS-deficient (APS(-/-)) mice were used to investigate its function in vivo. The blood glucose-lowering effect of insulin, as assessed ...

This paper proposes an algorithm for estimating the location of wireless access points (APs) in indoor environments to realize smartphone positioning based on Wi-Fi without pre-constructing a database. The proposed method is designed overcome main problem existing methods requiring advance construction database with coordinates or precise AP measurements. constructs local coordinate system firs...

HL-5 cells are cultured murine atrial cardiomyocytes and have been used in studies to address important cellular and molecular questions. However, electrophysiological features of HL-5 cells have not been characterized. In this study, we examined such properties using whole cell patch-clamp techniques. Membrane capacitance of the HL-5 cells was from 8 to 62 pF. The resting membrane potential wa...

Dual-frequency ultrasound (DFUS) has received considerable attention for enhanced inactivation of microbial pathogens medical treatment, but remains little investigated water disinfection. This study is focused on E. coli and faecalis in aqueous solution under dual-frequency ultrasonication at 120 + 1700 kHz using persulfate. Single-frequency ultrasonic showed the higher efficiency kHz, compare...

Photocatalytic water oxidation by persulfate (Na2 S2 O8 ) with [Ru(bpy)3 ](2+) (bpy=2,2'-bipyridine) as a photocatalyst provides a standard protocol to study the catalytic reactivity of water oxidation catalysts. The yield of evolved oxygen per persulfate is regarded as a good index for the catalytic reactivity because the oxidation of bpy of [Ru(bpy)3 ](2+) and organic ligands of catalysts com...

OBJECTIVE Persulfate salts are among the most frequently implicated causes of occupational asthma. The aim of this study was to describe the course of bronchial hyperresponsiveness and immunologic test results in patients with occupational asthma due to persulfate salts. PATIENTS AND METHODS Ten patients with occupational asthma due to persulfate salts were studied. Diagnosis was based on spe...

Catalytic persulfate technology is a new type of catalytic that has been extensively studied in recent years. Among them, the copper and silver materials synthesized by microwave assist have broad application prospects are class catalysts with excellent performance, environmental friendliness, stable structure. This article introduces material loaded metal activated carbon, analyzes mechanism o...