AIMS To identify the relative contribution of plasminogen activators, particularly tissue plasminogen activator (t-PA) and specific plasminogen activator inhibitors (PAI-1, PAI-2), to the fibrinolytic changes associated with various types of liver disease or severe chemical and physical damage to the liver. METHODS Platelet rich (PRP) and platelet poor plasma (PFP) from patients with alcoholi...

Abstract This study aims to determine the effect of activator-binder ratio on water absorption ambient-cured geopolymer concrete. Class F fly ash from Mpanau power plant was used as precursor. raw material activated by a mixture sodium silicate and hydroxide solution, with an 0,45; 0,50; 0,55; 0,60. Five percent replacement slaked lime added achieve ambient curing. The test specimen for is made...

Introduction: Stroke causes death and disability in patients throughout the world. At present, the only FDA- approved drug for ischemic stroke is recombinant tissue plasminogen activator (rt- PA). Unfortunately, rtPA can cause intracerebral hemorrhage and must use within limited time window (within 3-4.5 hour after onset of stroke). Ultrasound with rtPA loaded liposomes (rtPA_L...

The ZNF198/FGFR1 fusion kinase associated with an atypical myeloproliferative disease is constitutively activated and regulates several STAT transcription factors. We used oligonucleotide microarrays to compare the gene-expression profiles between HEK-293 cells that stably express either the ZNF198/FGFR1 chimeric protein or the wild-type ZNF198 gene. Expression of the plasminogen activator inhi...

ABSTRAKBertambahnya populasi penduduk berbanding lurus dengan kebutuhan infrastruktur, salah satunya meningkatnya beton yang berdampak buruk pada pencemaran lingkungan. Upaya untuk mengurangi tersebut adalah pembuatan ramah lingkungan geopolimer. Bahan utama geopolimer agregat dan binder terdiri dari fly ash alkali aktivator. Pada penelitian ini dilakukan analisis mengetahui pengaruh variasi ak...

We compared urokinase-type plasminogen activator (u-PA) in fluid phase and u-PA bound with its receptor on human blood monocytes with respect to proteolytic activity and susceptibility to inactivation by the plasminogen activator inhibitors PAI-1 and PAI-2. Receptor-bound u-PA is catalytically twice as efficient as fluid-phase u-PA. Fluid-phase u-PA is susceptible to rapid inhibition by PAI-1 a...