I.1. Definition I.2. What Is the Incidence and Outcome of Renal Failure in ICU Patients? I.3. Do Creatinine-clearance Markers and Other Biomarkers Help Identify Early Acute Renal Injury? I.4. How Should We Assess Renal Perfusion in an ICU Patient? I.5. Can We Predict which ICU Patient Will Develop Acute Renal Failure? II. What Can We Do to Protect against Developing Acute Renal Failure during R...

© 2011 Canadian Medical Association or its licensors CMAJ, July 12, 2011, 183(10) 1167 The initial management of episodes of acute renal failure is often done by clinicians who are not specialists in nephrology. Their efforts may be hampered by several factors, such as deficiencies in our understanding of acute renal failure, and consensus and anecdote forming the basis of much of our practice ...

GFR markers Among newer GFR markers in ARF, serum cystatin C deserves evaluation since it has been shown more sensitive and accurate than serum creatinine in several settings, but has not been validated as a GFR indicator in ARF (1-2). Another endogenous marker, β2-microglobulin, has been suggested as a GFR estimate (3). Measuring tubular enzymuria could facilitate the early detection of renal ...

Twelve patients with otherwise uncomplicated acute viral hepatitis (two were HBsAg-positive) developed renal failure. Apart from dehydration due to repeated vomiting in one patient, no factor responsible for precipitating renal failure could be identified. The clinical course was characterised by renal failure with plasma urea concentrations reaching maximum values of 26-69 mmol/l (175-416 mg/1...

BACKGROUND Clinical trials with N-acetylcysteine (NAC) in perioperative cardiovascular settings have shown inconsistent effects for renal endpoints. We aimed to systematically review these trials to ascertain its role in prevention of post-cardiovascular surgery acute renal failure. METHODS We searched MEDLINE, EMBASE, Cochrane Renal Health Library, and Google Scholar for randomized controlle...

Six patients with mitral stenosis complicated by renal artery embolism studied prospectively are presented. In five patients there was unilateral and in one patient bilateral renal artery involvement. The diagnosis was confirmed by intravenous pyelography, retrograde pyelography, renal angiography, renal scan or a combination of these. All had atrial fibrillation, proteinuria and elevated ...

background and objective: cystinosis is a rare inherited disease that leads to renal failure. fanconi syndrome is the major renal involvement in cystinosis patients. renal transplantation is the treatment of choice in cystinosis children with end-stage renal disease (esrd).  the study aimed to assess the outcome of renal transplantation in iranian children with cystinosis. methods: this retrosp...

AIMS To determine in a case-control study possible associations between the development of acute renal failure in preterm newborns and therapeutic interventions, particularly drug treatments. METHODS The study population was 172 preterm infants of <38 weeks gestation; 71 had acute renal failure and 101 were controls closely matched for gestational age and birth weight. Maternal and neonatal i...

1. Serial changes in plasma renin activity and plasma angiotensin levels were followed in rats during acute renal failure induced by mercuric chloride or glycerol. 2. During mercuric chloride-induced acute renal failure there were transitory large increases in plasma renin and angiotensin. In contrast, rats with acute renal failure produced by glycerol had a reduction in plasma renin and angiot...