many experimental studies have reported behavioral improvement after transplantation of peripheral nerve tissue into the contused spinal cord, even in large animals. the safety of this treatment in human remains unknown. in this translational phase 1 study, safety of peripheral nerve grafting for chronic spinal cord injuries and possible outcomes are being reported. twelve complete motor spinal...

the first necessary step in researches to treat spinal cord injuries (sci) is to understand complexities related to the neurophysiology and neurobiology changes of human sci with stem cell therapy(sct). the aim of this study is to identify these changes. the level of injuries is important in treatment and determination of this injury (whether it is complete, incomplete, or discomplete) is valua...

prevalence of spinal cord injury (sci) in iran is considerable and developing a national registry is substantial. registry can be a foundation of efforts for patient care improvement, clinical research facilitation, preventative strategy formulation and policymaking for better support of patients. with respect to long-term and multiple consequents of the lesions that will have a negative impact...

spinal cord injury (sci) leads to loss of nervous tissue and consequently to catastrophic neurological deficits. up to now there is no definite treatment available that restores the loss of function to a degree that an independent life can be guaranteed.this justifies the cost of research into the new modalities for a treatment of scis. in current paper, recent developments and new approaches i...

objectives: nowadays, spinal cord lesions, specially its injury, is one of the diseases/injuries that human-being is been affected by. it not only causes irreversible economical/social/cultural problems & uncompensated costs to the patient’s family & society but also, makes active peoples to inactive & needy ones. till now, there is no successful treatment for these patients so this ailment, it...

Neurological outcomes following spinal cord injury (SCI) are currently difficult to predict. While the initial American Spinal Injury Association Impairment Scale (AIS) grade can give an estimate o...

bone marrow mesenchymal stem cells can differentiate into neurons and astrocytes after transplantation in the spinal cord injury of rats. although bone marrow mesenchymal stem cells are known to protect against spinal cord injury through anti-apoptotic effects, but generation of neural stem cells with large number and safety protocols unclear. in the present study, described the differentiation...

MR imaging is increasingly used for the evaluation of patients with acute spinal injury because of its ability to noninvasively demonstrate parenchymal alterations involving the spinal cord as well as alterations involving surrounding osseous, soft-tissue, and ligamentous structures [1-4). The presence of epidural hematomas, disk herniation, or other epidural structural alterations that may cau...

s, letters, comments, editorials, reviews, or surveys Animal and in vitro studies Languages other than English Study published before 1995 No trauma (e.g., disease-related spinal cord lesions) Studies dealing with radiology protocols for cervical spine clearance Inclusion Criteria Studies were included if BOTH of the following criteria were met: Traumatic spinal cord injury or suspected spinal ...

Background & Aim: Disabilities resulting from road accidents, especially spinal cord injury, which often occur in the early or middle ages of life, cause psychiatric symptoms and worsen the quality of life in these people. The present study aimed to determine the role of depressed mood in the quality of life of patients with spinal cord injury in Guilan Province (in the north of Iran)...