نتایج جستجو برای: ada
تعداد نتایج: 20618 فیلتر نتایج به سال:
مقدمه: مطالعات متعددی دو معیار تشخیصی سازمان جهانی بهداشت (WHO) و انجمن دیابت آمریکا (ADA) را در تشخیص بیماران دیابتی مقایسه کردهاند. این مطالعه به عنوان یک تحقیق اپیدمیولوژی جمعیتی با هدف مقایسه این دو معیار در جمعیت شهری تهران طراحی شده است. مواد و روشها: 9229 فرد بالای 20 سال شرکتکننده در مطالعه قند و لیپید تهران, شامل 3870 مرد و 5359 زن بررسی شدند. افراد مبتلا به دیابت شناخته شده از مطال...
AIMS Idarucizumab, a humanized monoclonal anti-dabigatran antibody fragment, is effective in emergency reversal of dabigatran anticoagulation. Pre-existing and treatment-emergent anti-idarucizumab antibodies (antidrug antibodies; ADA) may affect the safety and efficacy of idarucizumab. This analysis characterized the pre-existing and treatment-emergent ADA and assessed their impact on the pharm...
IP3 receptors are channels that mediate the release of Ca(2+) from the intracellular stores of cells stimulated by hormones or neurotransmitters. Adenophostin A (AdA) is the most potent agonist of IP3 receptors, with the β-anomeric adenine contributing to the increased potency. The potency of AdA and its stability towards the enzymes that degrade IP3 have aroused interest in AdA analogs for bio...
Adenosine deaminase (ADA) deficiency causes severe combined immune deficiency (SCID) by interfering with the metabolism of deoxyadenosine, which is toxic to T lymphocytes at all stages of differentiation. Enzyme replacement with polyethylene glycol-modified ADA (PEG-ADA) has been previously shown to correct deoxyadenosine metabolism and improve mitogen-induced T lymphocyte proliferation. We stu...
BACKGROUND Tuberculous pleural effusion (TPE) is a paucibacillary manifestation of tuberculosis, so isolation of Mycobacterium tuberculosis is difficult, biomarkers being an alternative for diagnosis. Adenosine deaminase (ADA) is the most cost-effective pleural fluid marker and is routinely used in high prevalence settings, whereas its value is questioned in areas with low prevalence. The lymph...
The study was done to evaluate the ADA activity in the diagnosis of pulmonary tuberculosis and its relationship with clinical, radiological and laboratory parameters. The study was carried out on 142 patients suspected from various pulmonary disorders from July 2008 to January 2009. Forty five normal healthy individuals were included as control subjects for ADA evaluation. Four groups of patien...
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