Background: Vaginal epithelium is the most important site for initial contact of the parasite infection in humans. Objective: To investigate the effect of Lactobacillus acidophilus (LA) and pH on attachment of T. vaginalis isolated from symptomatic and asymptomatic patients to vaginal epithelial cells (VECs). Methods: Following 1-4 hrs contact of parasite with VECs, wet mounts were prepared and...

Recently, leucine-rich repeat transmembrane proteins (LRRTMs) were found to be synaptic cell-adhesion molecules that, when expressed in nonneuronal cells, induce presynaptic differentiation in contacting axons. We now demonstrate that LRRTM2 induces only excitatory synapses, and that it also acts to induce synapses in transfected neurons similarly to neuroligin-1. Using affinity chromatography,...

Leukemia cutis is a localized or disseminated skin infiltration by leukemic cells. A 64-year-old man was diagnosed with acute myeloid leukemia (AML) complicated by disseminated intravascular coagulation. During the course of treatment with gabexate mesilate, the substance accidentally leaked from the infusion site in his elbow. One month later, a dark red erythema and induration accompanied by ...

Vascular endothelial cells rapidly sense and transduce external forces into biological signals through a process known as mechanotransduction. Numerous biological processes are involved in mechanotransduction, including calcium signaling and activation of focal adhesion sites, but little is known about how cells initially sense changes in the external mechanical environment. In order to examine...

background and objective: probiotics are live microbial feed supplements which beneficially affect the host animal by improving its intestinal microbial balance, producing metabolites which inhibit the colonization or growth of other microorganisms or by competing with them for resources such as nutrients or space. the aim of this study was to investigate the probiotic properties of candida fam...