Sebaceous carcinomas (SC) are rare adnexal tumors with possible aggressive behavior usually arising in the head and neck region of adults in the seventh decade of life. Treatment has traditionally been with surgical excision with 5-6 mm wide margins but Mohs micrographic surgery (MMS) has also been reported as an effective treatment modality. We present a case of a Caucasian female renal transp...

The benign precursor usually antedates the malignancy by many years, as a non-progressive verrucous lesion; and when congenital, there is a frequent association with naevus sebaceous. In older people, the presence of solitary cutaneous adenocarcinoma leads to clinical consideration of a metastatic versus primary cancer; systematic morphologic analysis, will usually resolve the issue, as illustr...

INTRODUCTION Breast cancer is common in women and its metastases involve the skin in approximately one quarter of patients. Accordingly, metastatic breast cancer shown to be cutaneous through histology must be distinguished from a wide variety of other neoplasms as well as the diverse morphologic variants of breast cancer itself. CASE PRESENTATION We report the case of a 61-year-old Caucasian...

Eccrine syringofibroadenoma (ESFA) is an uncommon benign adnexal neoplasm which derives from cells of the acrosyringium of eccrine sweat glands. The clinical appearance is nonspecific but the histological features are typical. Five clinical subtypes of ESFA exist: (1) solitary ESFA; (2) multiple ESFA associated with ectodermal dysplasia; (3) multiple ESFA without cutaneous features; (4) unilate...

Fibroid is a common benign neoplasm more often located in the uterus and less commonly seen adnexa other supporting structures of like broad uterosacral ligament. The incidence extra uterine leiomyomas <1%. A 48-year-old female para one live presented with chief complaints mass per abdomen for 2 years prolonged heavy bleeding 15 days. Based on clinical radiological findings, diagnosis tubo-o...

Background Microcystic adnexal carcinoma (MAC) is a rare skin neoplasm that has not been characterized on molecular basis. Aim To assess expression profiles of Hedgehog (HH) signalling molecules in MAC and control tumours. Methods Immunohistochemistry was performed for Sonic (SHH), Indian (IHH), Patched 1 (PTCH1) Smoothened (SMO) patient tissue (n = 26) tumour tissue, including syringoma (SyG; ...

Poroma is a rare benign neoplasm that derives from eccrine sweat glands epithelium. Its histological subtypes, with respect to its position within skin layers, are eccrine poroma, hidroacanthoma simplex, poroid hidradenoma, and dermal duct tumor. Poromas commonly exhibit benign clinical behavior as they are usually small and asymptomatic and do not exhibit malignant behavior. Although their his...

OBJECTIVE Our purpose was to describe pregnancy-associated adnexal masses in eastern North Carolina. STUDY DESIGN A retrospective study was performed of 60 adnexal masses resected during pregnancy at a regional referral hospital from January 1990 to March 2002. RESULTS Adnexal masses occurred in 0.15% of pregnancies. Average gestational age at diagnosis and surgery was 12 and 20 weeks, resp...

Adnexal masses can be found in 0.19 to 8.8% of all pregnancies. Most masses are functional and asymptomatic and up to 70% resolve spontaneously in the second trimester. The main predictors of persistence are the size (>5 cm) and the imagiological morphocomplexity. Those that persist carry a low risk of malignancy (0 to 10%). Most malignant masses are diagnosed at early stages and more than 50% ...

Gastrointestinal stromal tumours are mesenchymal neoplasms of the gastrointestinal tract.1 This case study reports the incidental finding of a left sided adnexal mass in a woman with twin pregnancy. The presence of any mass during pregnancy raises issues for patient management, the effect on the developing fetus and mode of delivery.