background: mature landfill leachate is a complicated mixture which is resistant to biological treatment processes. the treatment of mature landfill leachate by struvite precipitation and fenton oxidation was the main objective of the current research. methods: struvite with the phosphate/ammonia/magnesium molar ratio of 1/1/1.05 was considered during all experiments. five initial phs of 3, 4, ...

Protein glycation adducts, early glycation adducts, such as N(epsilon)-fructosyl-lysine, and advanced glycation end products (AGEs) are uremic toxins. Glycation adducts are found in plasma and tissue proteins (glycation adduct residues), in peptides (glycation adduct peptide residues), and glycated amino acids (glycation free adducts). The latter two analyte groups arise from proteolysis of gly...

Compared to other cyclooxygenase-2 inhibitors, celecoxib is associated with a lower cardiovascular risk, though the mechanism remains unclear. Angiotensin II is an important mediator of oxidative stress in the pathophysiology of vascular disease. Cyclooxygenase-2 may modify the effects of angiotensin II though this has never been studied in humans. The purpose of the study was to test the effec...

BACKGROUND Measuring the effects of the acute intake of natural products on human biomarker concentrations, such as those related to oxidation and inflammation, can be an advantageous strategy for early clinical research on an ingredient or product. METHODS 31 total healthy subjects were randomized in a double-blinded, placebo-controlled, acute pilot study with post-hoc subgroup analysis on 2...

conclusions contrast-agent-induced nephropathic changes are more closely related to the magnitude of lipid peroxidation than protein oxidation. results compared with the control group, groups cin and n + cin had significantly higher urea and lhp levels (p < 0.05 and p < 0.001, respectively) and significantly lower cu, zn-sod activity and creatinine clearance (p < 0.05). there was no statistical...

Advanced oxidation protein products (AOPPs), a protein biomarker of increased oxidative stress, are elevated in uremic patients. Zhou et al. demonstrate that chronic administration of AOPPs induces podocyte apoptosis and proteinuria in normal rats via a cascade of signaling events. This study for the first time establishes a causative link between oxidative stress and podocyte depletion and cou...