نتایج جستجو برای: adverse drug reactions adrs
تعداد نتایج: 850498 فیلتر نتایج به سال:
GOAL Inappropriate prescribing of a multiple therapeutic agents to patients with chronic conditions is very common in everyday practice. Adverse drug reactions (ADRs) are still considered as one of the main problems of drug therapy. We investigated idiosyncratic symptoms and signs of adverse drug reactions (ADRs) of the most frequent used combination of drugs among hospitalized patients prescri...
Adverse drug reactions (ADRs) are an important health issue. While prevalence and risk factors associated with ADRs in the general adult population have been well documented, much less is known about ADRs in the elderly population. The aim of this study was to review the published literature to estimate the prevalence of ADRs in the elderly in the acute care setting and identify factors associa...
OBJECTIVE To estimate the incidence of serious and fatal adverse drug reactions (ADR) in hospital patients. DATA SOURCES Four electronic databases were searched from 1966 to 1996. STUDY SELECTION Of 153, we selected 39 prospective studies from US hospitals. DATA EXTRACTION Data extracted independently by 2 investigators were analyzed by a random-effects model. To obtain the overall incide...
thrombolytic agents are among the medications that are used widely for the treatment of thromboembolic disorders and myocardial infarction (mi). despite the world-wide availability of newer specific agents, streptokinase (sk) is still the most frequently used medication from this class in iran. hence we conducted this study to review the adverse reactions to this medication which were reported ...
Detection of adverse drug reactions (ADRs) in hospitals provides an important measure of the burden of drug related morbidity on the healthcare system. Spontaneous reporting of ADRs is scare and several obstacles to such reporting have been identified formerly. This study aimed to determine the role of clinical pharmacy residents in ADR reporting within a hospital setting. Clinical pharmacy res...
Background HIV-infected patients have a higher risk of developing hematological adverse drug reactions (ADRs) than the general population and have a significant impact on patients’ current and future care options. The study was to determine the causality, the incidence rate, severity pattern of occurrence of hematological ADRs associated with highly active antiretroviral therapy in HIV positive...
Drugs are chemical substances, which can, on consumption and under certain conditions, be toxic and cause Adverse Drug Reactions (ADRs) in patients. This paper puts forth the proposition of generating a systemic alert to a clinician, at the time of placing a medication order for a patient, when the number of ADRs associated with the selected medication is significantly different from the number...
It is difficult to determine adverse drug reactions (ADRs) in daily complicated clinical practice in which many kinds of drugs are prescribed. We evaluated how well the Naranjo Algorithm (NA) categorized ADRs among suspected ADRs. The Japan Adverse Drug Events (JADE) study was a prospective cohort study of 3459 inpatients. After all suspected ADRs were reported from research assistants, a singl...
Adverse drug reactions (ADRs) present a major concern for drug safety and are a major obstacle in modern drug development. They account for about one-third of all late-stage drug failures, and approximately 4% of all new chemical entities are withdrawn from the market due to severe ADRs. Although off-target drug interactions are considered to be the major causes of ADRs, the adverse reaction pr...
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