Although the adverse effects of maternal aging on reproductive outcomes have been investigated widely, there is no consensus on the impact of paternal age. Therefore, we investigated the effect of paternal age on reproductive outcomes in a retrospective analysis of 9,991 in vitro fertilization (IVF) cycles performed at the Reproductive Medicine Center of the Third Affiliated Hospital of Guangzh...

OBJECTIVES To present long-term outcome and to identify predictors of seizure freedom after vagus nerve stimulation (VNS). METHODS All patients who had undergone VNS implantation in the Epilepsy Centre Bethel were retrospectively reviewed. There were 144 patients who had undergone complete presurgical evaluation, including detailed clinical history, magnetic resonance imaging, and long-term v...

OBJECTIVE To characterize speech perception performance in elderly cochlear implant users compared with younger adult users. DESIGN Case-control retrospective analysis from January 1, 1999, to January 28, 2008. SETTING Tertiary care, academic practice cochlear implant program. PATIENTS Medical records for 78 patients with age at implantation of 65 years or older were analyzed for ear-spec...

The causes of the decline in implantation rates observed with increasing maternal age are still a matter for debate. Data from oocyte donation strongly suggest that in women of advanced reproductive age, the ability to become pregnant is largely unaffected while oocyte quality is compromised. The incidence of chromosomal abnormalities in embryos is considerably higher than that reported in spon...

BACKGROUND AND PURPOSE Mesenchymal stem cells have potential as a regenerative therapy in ischemic stroke. We sought to determine MR imaging findings after mesenchymal stem cell implantation in chronic middle cerebral artery infarcts and to compare brain volume changes in patients with mesenchymal stem cells with those in age-matched healthy controls and controls with chronic stable MCA infarct...

OBJECTIVES To examine the variables affecting outcomes for sequential bilateral cochlear implantation patients in the adolescent population. STUDY DESIGN Retrospective chart review at tertiary care center. METHODS Main outcome measures were open set speech recognition tests at the word (Consonant-Nucleus-Consonant/Phonetically Balanced Kindergarten List Test [CNC/PBK]) and sentence levels i...

Thirty children with cochlear implants (CI children), age range 3-12 years, and 30 children with normal hearing (NH children), age range 4-6 years, were tested on theory of mind and language measures. The CI children showed little to no delay on either theory of mind, relative to the NH children, or spoken language, relative to hearing norms. The CI children showed a slightly atypical sequence ...

OBJECTIVES Children are undergoing cochlear implantation younger than ever before. There has been some concern that young children may have an increased risk of soft tissue complications than older age groups. We aim to review the major and minor soft tissue complications after pediatric cochlear implantation in the age group of younger than 12 months. STUDY DESIGN Retrospective case review. ...

How well do hearing-impaired children speak after a Cochlear Implantation (CI) and how does their language acquisition proceed? The answer to these questions is inevitably that success depends on a number of factors: one of the critical factors is the age at implantation. In this paper we provide an overview of the phonological results of a longitudinal study of nine early-implanted Dutch speak...