Activity of Alkyl Hydroperoxide Reductase Subunit C1 and C2 of Vibrio 1 parahaemolyticus against Different Peroxides 2 3 Chun-Hui Chung, Tsung-yong Ma, Shin-yuan Fen, and Hin-chung 4 Wong* 5 6 Department of Microbiology, Soochow University, Taipei, Taiwan 111, 7 Republic of China 8 9 Running title: AhpC of Vibrio parahaemolyticus 10

This report describes N-terminal group analysis of six new proteins isolated from in vivo-grown Mycobacterium leprae, three of which correspond to products of the cysA, ahpC, and rpIL genes, which were recently defined through the M. leprae genome project and which encode a putative sulfate sulfurtransferase, an antioxidant enzyme, and the L7/L12 ribosomal protein, respectively.

Many eubacterial genomes including those of Salmonella typhimurium, Streptococcus mutans, and Thermus aquaticus encode a dedicated flavoprotein reductase (AhpF, Nox1, or PrxR) just downstream of the structural gene for their peroxiredoxin (Prx, AhpC) homologue to reduce the latter protein during turnover. In contrast, the obligate anaerobe Clostridium pasteurianum codes for a two-component redu...

Legionella pneumophila expresses two catalase-peroxidase enzymes that exhibit strong peroxidatic but weak catalatic activities, suggesting that other enzymes participate in decomposition of hydrogen peroxide (H2O2). Comparative genomics revealed that L. pneumophila and its close relative Coxiella burnetii each contain two peroxide-scavenging alkyl hydroperoxide reductase (AhpC) systems: AhpC1, ...

In the last decade, there were 10 million new tuberculosis cases per year globally. Around 9.5% of these cases were caused by isoniazid resistant (INHr) Mycobacterium tuberculosis (Mtb) strains. Although isoniazid resistance in Mtb is multigenic, mutations in the catalase-peroxidase (katG) gene predominate among the INHr strains. The effect of these drug-resistance-conferring mutations on Mtb f...

In growing pigs, the feed cost accounts for more than 60% of total production costs. The determination of efficiency of energy utilization through calorimetry measurements is of importance to sustain suitable feeding practice. The objective of this paper is to describe a methodology to correct daily heat production (HP) obtained from measurements in respiration chamber for the difference in ene...

In this study we report the identification and role of the alkyl hydroperoxide reductase (ahp) gene in Bacteroides fragilis. The two components of ahp, ahpC, and ahpF, are organized in an operon, and the deduced amino acid sequences revealed that B. fragilis AhpCF shares approximately 60% identity to orthologues in other gram-positive and gram-negative bacteria. Northern blot hybridization anal...