Camptothecin, an antitumor drug that specifically targets topoisomerase I, induced IW32 erythroleukemia cells to differentiate along the erythroid pathway, as demonstrated by the increased mRNA and protein expression of hemoglobin. Unlike other chemically induced erythroleukemia cell differentiation, no c-myc mRNA down-regulation was observed in the early phases of drug treatment. Among the hem...

An experiment was performed to investigate the progressive changes of the anemia caused by excess methionine in rats, during the developmental and convalescent periods. Hemoglobin concentration, hematocrit value and red blood cell count were elevated in the initial stage of excess methionine feeding, they then gradually decreased. During the convalescent period, after ceasing administration of ...

In this paper, we propose an Augmented Lagrangian Affine Scaling (ALAS) algorithm for general nonlinear programming, for which a quadratic approximation to the augmented Lagrangian is minimized at each iteration. Different from the classical sequential quadratic programming (SQP), the linearization of nonlinear constraints is put into the penalty term of this quadratic approximation, which resu...

Ecdysteroids are steroid hormones that induce molting and determine developmental timing in arthropods. In insect larva, the prothoracic gland (PG) is a major organ for ecdysone synthesis and release. Released ecdysone is converted into the active form, 20-hydroxyecdysone (20E) in the peripheral tissues. All processes from ecdysone synthesis and release from the PG to its conversion to 20E are ...

The effect of In surface segregation on the microstructure of short period superlattices ~SPSs! in two different material systems with nominally equivalent lattice misfit, AlAs/InAs and GaAs/InAs, has been investigated and compared. It was found that the quality of the SPSs and the appearance of lateral composition modulation are remarkably different in these two systems. For AlAs/InAs SPSs gro...

Gallium arsenide is an outstanding nonlinear optical material, thanks to its high second-order nonlinear coefficient, wide transparency in the infrared, and possibility of integration with sources. However, phase matching for nonlinear frequency conversion is difficult to achieve in this isotropic, highly dispersive semiconductor. Although quasimatching by domain reversal was recently demonstra...