OBJECTIVE Approximately 50% of patients with alcohol dependence experience alcohol withdrawal. Severe alcohol withdrawal is characterized by seizures and/or delirium tremens, often refractory to standard doses of benzodiazepines, and requires aggressive treatment. This review aims to summarize the literature pertaining to the pharmacotherapy of severe alcohol withdrawal. DATA SOURCES PubMed (...

OBJECTIVE To assess the effect of an individualized treatment regimen on the intensity and duration of medication treatment for alcohol withdrawal. DESIGN A randomized double-blind, controlled trial. SETTING An inpatient detoxification unit in a Veterans Affairs medical center. PATIENTS One hundred one patients admitted for the treatment of alcohol withdrawal who could give informed conse...

ERSTAD, B. L. & COTOGNO,C. L. (1995) Management of alcohol withdrawal. American Journal of Health-System Pharmacy. 52. 697-709. HESSIONM. A.. VERMA.S. & MOHANBHAKTA,K. G. (1979) Dependence on chlormethiazole and effects of its withdrawal. Lancet, i. 953-954. KAIM.S. C.. KLETT.C. J. & ROTHFELD. B. (1969) Treatment of the acute alcohol withdrawal state: a comparison of four drugs. American Journa...

Aims: The present study examined the effects of protracted alcohol withdrawal on affectivity, craving, selective attention and executive functions (EFs) in alcohol-dependent patients.Methods: Selective attention (The D2 Cancellation Test), flexibility (Trail Making Test), inhibition (Stroop Task), decision making (Iowa Gambling Task), craving (Obsessive–Compulsive Drinking Scale) and state affe...