Context: Considering the increasing prevalence of obesity and insulin resistance syndrome worldwide, non-alcoholic fatty liver disease (NAFLD) has become a major health concern. Early diagnosis and proper management might prevent disease progression. The aim of this article is to review the current knowledge on the diagnosis and evaluation of disease severity in NAFLD. Evidence Acquisition: Aft...

Background and objectives: Non-alcoholic fatty liver disease (NAFLD) is a common liver condition. On the other hand, coffee consumption has shown promising for gastrointestinal diseases.  Detection of the most valuable biomarkers of decaffeinated coffee treatment in healthy and non-alcoholic fatty liver disease conditions was the aim of the present study. Methods:</stro...

Non-alcoholic fatty liver disease (NAFLD) incorporates an extensive spectrum of histologic liver abnormalities, varying from simple triglyceride accumulation in hepatocytes non-alcoholic fatty liver (NAFL) to non-alcoholic steatohepatitis (NASH), and it is the most frequent chronic liver disease in the industrialized world. Beyond liver related complications such as cirrhosis and hepatocellular...

Non-alcoholic fatty liver had been believed to be a non-progressive benign disease. However, Ludwig et al. described some patients who exhibited progressive steatohepatitis without habitual alcohol drinking (Ludwig et al., 1980) and referred to this disease as non-alcoholic steatohepatitis (NASH). Later, NASH and non-progressive simple steatosis patients were included in the single disease enti...

Non-alcoholic liver disease(NAFLD) is a common liver disorder which is closely associated with insulin resistance and type 2 diabetes mellitus and it is characterised by fat accumulation in the liver.The prevalence in diabetic population is found to be 20-40%. Studies have shown that NAFLD is strongly associated with severalmetabolic disordersand diseases, such as obesity, type 2 diabetes melli...

Non-alcoholic fatty liver disease (NAFLD) is the term used to describe the alcohol-like liver injury that occurs in the absence of alcohol abuse. It involves a range of histological abnormalities including simple steatosis or fatty liver, non-alcoholic steatohepatitis (NASH) and NAFLD induced cirrhosis. The predominant risk factor for NAFLD appears to be insulin resistance. Simple steatosis and...

Background: Non-alcoholic fatty liver disease (NAFLD) has become over the last decade the most common form of chronic liver disease in children and adults. It is tightly associated with obesity and threatens to become a serious public health problem. Non-alcoholic steatohepatitis (NASH) is also commonly associated with type 2 diabetes mellitus (DM). Therefore, this study was carried out to know...

results the relative expression of mtdna copy number was 3.7 fold higher in nafld patients than healthy controls (p < 0.0001). the results remained significant after adjustment for age, bmi, and gender (p = 0.02). in addition, the mtdna copy number was 4.3 (p < 0.0001) and 3.2-fold (p < 0.0001) higher in nonalcoholic fatty liver (nafl) and non-alcoholic steatohepatitis (nash) patients than heal...

Non-alcoholic fatty liver disease (NAFLD) is an emerging public health problem globally. NAFLD one of the most common diseases worldwide and cause abnormal enzymes in many developed countries. estimated to afflict approximately 1 billion individuals worldwide. An 20-30 % general population afflicted from it In India could be a silent epidemic with its prevalence ranging 9-32%. Studies have show...