Objective: To study the level of serum alkaline phosphatase in diabetic patients with periodantitis and compare to control group. Material and Methods: This study was carried out in Pathology Department Gomal Medical College Dera Ismail Khan, from Jan. 2006 to June 2007. Subjects of type-2 diabetes mellitus having periodontitis (group A), diabetics without periodontitis (group B), non-diabetics...

The hepatoprotective activity of a fraction of the leaf extract of A.indica against carbon tetrachloride : liquid paraffin (1:1) induced liver damage in rats at doses of 100 mg/kg and 200 mg/kg was evaluated. A significant dose dependent hepatoprotective activity was evidenced by lowering of the elevated levels of glutamate oxaloacetate transaminase (GOT), glutamate pyruvate transaminase (GPT),...

The content of alkaline phosphatase (ALP) was determined in neutrophils isolated from patients with acute bacterial infections by a standard enzyme assay. Compared with control cells, patient cells exhibited about a fivefold increase in ALP activity. There was no difference between the ALP Km values of control and patient cells, which indicates that the elevated activity in patient cells was du...

BACKGROUND AND PURPOSE Higher serum alkaline phosphatase (ALP) and phosphate levels are associated with atherosclerotic disease and an increased risk of cardiovascular events. However, the association of ALP/phosphate with cerebral atherosclerosis and prognosis in patients with acute stroke is not well known. METHODS In 1034 patients with first-ever acute cerebral infarction, levels of ALP an...

The alkaline phosphatase (ALP) assay is a rapid and convenient method for verifying milk pasteurization. Since colorimetric ALP assays rely on subjective visual assessments, their results are especially unreliable near the detection limits. In this study, we attempted to establish quantitative criteria for residual ALP in milk by using a more objective method based on spectrophotometric measure...

A novel alkaline phosphatase (S-ALP) was found in the culture filtrate of Streptomyces hiroshimensis IFO 12785. Purification was achieved on Sephadex G-75 column, palmitoylated gauze column, and Superdex 75 HR column chromatographies. The molecular weight of S-ALP was estimated to be 14200 by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE). The isoelectric point is 9.2. S-A...

We studied the temporal and quantitative relation between bone alkaline phosphatase (ALP) and height velocity in 62 short normal children as part of a prospective randomized study to compare placebo, growth hormone, oxandralone, and testosterone, singly and in combination, in promoting short-term growth acceleration and increased final height. The pretreatment cross-sectional correlation betwee...

the objective of this study was to investigate aspartate-amino-transferase (ast), γ-glutamyl-transferase(ggt), alkaline phosphatase (alp), lactate-dehydrogenase (ldh) and acid phosphatase (acp) activities andsemen parameters (volume, ph, concentration, total sperm number (tsn), progressive motility, dead sperm,total morphological defect (tmd) and hypo-osmotic swelling test (host)) in seminal pl...

The fresh water field crab, Spiralothelphusa hydrodroma is an important food source in parts of South India. The impact of cypermethrin on the variations in the enzyme activity of gills and hemolymph of the experimental female crab S. hydrodroma was carried out. The toxicity of the cypermethrin on the crab was estimated using LC50. Quantitative enzymatic studies of lactate dehydrogenase (LDH), ...

Since the 1960s membrane-bound enzyme alkaline phosphatase (ALP) has been utilized in drug delivery. As it cleaves phosphate substructures from drugs, auxiliary agents, and even surface of nanocarriers, this enables design delivery systems that can alter their properties body on demand. Anionic nanocarriers exhibiting bioinert to interactive once having reached target site as due an ALP-trigger...