Self-incompatibility (SI) is a genetic mechanism in many flowering plants by which generative reproduction prevented. The self-incompatibility caused the functions of cell controlled genes called S or genes. results decreased pollination and ultimately yield loss. In apple (Malus domestica L.), multi-allelic S-locus. Approaches S-glycoprotein profiles allele-specific PCR methods using gene for ...

The search for somatic mutations that drive the initiation and progression of human tumors has dominated recent cancer research. While much emphasis been placed on characterizing prevalence function driver mutations, comparatively less is known about their serial genetic evolution. Indeed, study this phenomenon largely focused tumor-suppressor genes recessive at cellular level or mechanisms res...

Background: The tumor suppressor gene TP53 (alias p53) located on chromosome 17 is involved in various cancers. Case-control studies have shown that p53 codon 72 polymorphism modulates the prognosis and susceptibility to various malignancies. We undertook the present study to explore a possible association between mucinous and non-mucinous adenocarcinomas with different genotypes or alleles at ...

A two-type two-sex branching process is considered to model the evolution of number carriers an allele and its mutations a Y-linked gene. The limiting growth rates different types couples males (depending on allele, mutated or not, that they carry on) set coexistence both alleles fixation mutant are obtained. In addition, genotype gene sex frequencies those sets established. Finally, main resul...