Heliotropium indicum is used traditionally as a remedy for conjunctivitis in Ghana. This study therefore evaluated the antiallergic potential of an aqueous whole plant extract of Heliotropium indicum (HIE) in ovalbumin-induced allergic conjunctivitis and attempted to predict its mode of action. Clinical scores for allergic conjunctivitis induced by intraperitoneal ovalbumin sensitization (100 :...

Allergic conjunctivitis affects approximately 15% of the global population and has a higher prevalence of about 40% in industrialized countries such as the United States. Seasonal allergy sufferers present with a variety of signs and symptoms, but patients frequently report that ocular allergy symptoms are the most bothersome. Many topical ocular prescription therapies are available and are inc...

Allergic conjunctivitis (AC) represents a spectrum of disorders, comprising seasonal allergic conjunctivitis (SAC), perennial allergic conjunctivitis (PAC), atopic keratoconjunctivitis (AKC), vernal keratoconjunctivitis (VKC) and giant papillary conjunctivitis. Of these ocular allergy types, SAC and PAC are the most common.The most striking difference within this group of ocular diseases is tha...

The definition, classification, pathogenesis, test methods, clinical findings, criteria for diagnosis, and therapies of allergic conjunctival disease are summarized based on the Guidelines for Clinical Management of Allergic Conjunctival Disease (Second Edition) revised in 2010. Allergic conjunctival disease is defined as "a conjunctival inflammatory disease associated with a Type I allergy acc...

Background: Vataja Abhishyanda is characterized by Toda (Pricking pain), Sangharsha (foreign body sensation), Achchasruta (watery discharge), Alpa Shopha (mild chemosis), Vishushka Bhava (feeling of dryness), Parushya (roughness) etc which are very similar to the most signs and symptoms Allergic Conjunctivitis. It one common type eye allergy widely experienced global population. Aims Objective:...

Ligneous conjunctivitis is a rare form of chronic pseudomembranous conjunctivitis that is associated with systemic membranous pathological changes. A probable link between plasminogen and ligneous conjunctivitis has been indicated by the recent diagnoses of plasminogen deficiency in five patients suffering from ligneous conjunctivitis. The current study reports that plasminogen-deficient mice d...

PURPOSE To evaluate the efficacy of using topical cyclosporin A 0.05% (Restasis) for the treatment of paediatric allergic conjunctivitis. METHODS This retrospective study included consecutive cases of paediatric allergic conjunctivitis treated with Restasis between 2010 and 2013. Subjects with follow-up time less than 3 months after using Restasis were excluded. Itch severity score, symptom s...

PURPOSE To investigate the immunosuppressive effects of mucosal immune therapy in experimental allergic conjunctivitis. METHOD We used 11 white Hartrey guinea pigs divided into two groups. Six animals (treated group) received pretreatment with topical instillation of cholera toxin B (4 micrograms/30 ml) and ovalbumin (10 micrograms/30 ml). The other group of 5 animals served as control. All t...

Results At the age 20 years, atopic eczema was equally common despite of atopic heredity. Allergic rhinitis was significantly (p=0.004) more common in children prone to atopy. Atopic eczema at age 2, 7 and 18 years flagged atopic eczema lasting until young adulthood, and predicted later rhino conjunctivitis (60%) and asthma at age 20y (28%). Timothy grass (65%) and birch pollen (55%) sensitizat...