Objective: As a global health problem, allergic rhinitis accounts for several psychological disorders including fatigue, mood changes, depression, anxiety, and disrupted quality of life. How people cope with the symptoms of the disease is of an utmost importance.  The present research is pioneering in comparing the quality of life, psychological state and cognitive emotion regulation strategies...

background: black seed (bs) is used in traditional medicine as a therapy for a variety of diseases including allergic asthma. materials and methods: in the present study, anti-inflammatory and immunomodulatory effects of bs on cytokine gene expression, lung airway eosinophilia and goblet cell hyperplasia were examined in a mouse mice model of allergic asthma. groups of 6-week-old female balb/c ...

INTRODUCTION The microbiota controls a variety of biological functions, including immunity, and alterations of the microbiota in early life are associated with a higher risk of developing allergies later in life. Several probiotic bacteria, and particularly lactic acid bacteria, were described to reduce both the induction of allergic responses and allergic manifestations. Although specific prob...

IL-5-induced chemotaxis of eosinophils is an important feature of allergic airway inflammatory diseases. Simvastatin, a lipid lowering agent, has been shown to exhibit anti-inflammatory and anti-allergic effects. Our aim was to investigate the effect of simvastatin on IL-5-induced eosinophil chemotaxis and its regulatory mechanisms. Eosinophils were derived by treating HL-60 clone 15 (HC15) cel...

the first epidemiologic survey of childhood allergic rhinitis in iran was carried out from may 1995 until april 1996.. a questionnaire was distributed among 4584, 11-15 year-old children of both sexes, to be completed under supervision of medical students. nasal smears were collected from the cases with allergic rhinitis (n = 445, 5.8%.), and from 340 healthy children for comparison. significan...

background: allergic diseases including asthma, allergic rhinitis (ar) and eczema are common chronic diseases in children. the purpose of this study was to determine the prevalence of asthma, ar and eczema in sari, iran. methods: this study was carried out on all elementary schools selected as a cluster from february 2010 to july 2010 in sari, north of iran. a questionnaire was provided accordi...

BACKGROUND Allergic rhinitis (AR) is the most common allergic disease but little is known about the difference of local immune responses in children and adults with AR. OBJECTIVE To compare local immune responses between children and adults with AR and nonallergic rhinitis (NAR), and to investigate whether the association of local and systemic immune responses is different between the two age...