conclusions increased serum levels of interleukins 6 and 8 as a predictive marker might be associated with unfavorable clinical outcome in patients with severe tbi. results comparing the serum levels of interleukins in two groups with favorable and unfavorable clinical outcomes showed that the mean serum levels of interleukins 6 and 8 in group with favorable outcome was 85.2 ± 51.6 and 52.2 ± 3...

5. Anderson RC: Fetal and infant death, twinning and cardiac malformations in families of 2000 children with and without cardiac defects. Am J Cardiol 38: 218, 1976 6. Nora JJ, Nora AH: Genetics and Counseling in Cardiovascular Diseases. Springfield, Charles C Thomas, in press 7. Nora JJ, Nora AH, Sinha AK: The Ullrich-Noonan syndrome (Turner phenotype). Am J Dis Child 127: 48, 1974 8. Nora JJ,...

holt-oram syndrome is an autosomal dominant disorder, characterised by skeletal abnormalities of the upper limb associated with congenital heart defect, mainly atrial and ventricular septal defects. skeletal defects exclusively affect the upper limbs in the preaxial radial ray distribution and are bilateral and asymmetrical. they range from clinodactyly, absent or digitalised thumb, hypoplastic...

Anomalous origin of the left coronary artery from the pulmonary artery (ALCAPA) is a rare congenital cardiac malformation. We report three cases of ALCAPA who survived to adulthood. The first case was a 51-year-old woman who complained of typical chest pain that was diagnosed with ALCAPA using cardiac catheterization and coronary computed tomographic angiography (CTA). The second case was a 30-...

Exercise testing in adult cardiac patients has mainly focused on ischaemic heart disease. The results of exercise testing with ECG monitoring are often helpful in diagnosing the presence of significant coronary artery disease. In children with heart disease, the type of pathology is different. Ischaemic heart disease is very rare. The majority of patients will present with congenital heart defe...

Assembly and mutual proximities of alpha, beta, and gamma(c) subunits of the interleukin 2 receptors (IL-2R) in plasma membranes of Kit 225 K6 T lymphoma cells were investigated by fluorescence resonance energy transfer (FRET) using fluorescein isothiocyanate- and Cy3-conjugated monoclonal antibodies (mAbs) that were directed against the IL-2R alpha, IL-2R beta, and gamma(c) subunits of IL-2R. ...

Congenital sternal cleft is a rare abnormality resulting from fusion failure of sternum. It occurs in isolation or along with defects of abdominal wall, diaphragm, pericardium, and heart. Early surgical correction is required to protect the underlying structures for risk of cardiac compression. Here we report a case of 20-day female child presenting with congenital sternal cleft associated with...

Background: Objective of the study was to provide insight on immune response in patients rheumatic heart disease, mitral stenosis and evaluation various cytokines pulmonary hypertension secondary disease.Methods: Total 163 subjects, more than 18 year age, were enrolled this study. 84 subjects with (group A) diagnosed two-dimensional echocardiography (2D echo) 79 normal healthy volunteers B). Pa...

Congenital heart disease occurs in two or more members of a family more often than can be accounted for by chance. Campbell (1959) found the condition to occur less commonly in parent and child than in sibs, and it occurs much less frequently in three generations, but he had two such families in his series: in one the girl, her mother, and grandmother all had atrial septal defects; in the other...