The ethanolic extract and its chloroform soluble and chloroform insoluble fractions of the roots of Baliospermum montanum were investigated in albino rats to evaluate the analgesic activity. Tailo - flick animal model was employed to test analgesic activity and compaired with a standard drug, Diclofenac sodium. The results indicate that the ethanolic extract and its chloroform soluble fraction ...

Linum usitatissimum L is traditionally used for relief of pain and inflammation. In this study, the analgesic and anti-inflammatory effects of this plant were evaluated. Xylene test was used for anti-inflammatory evaluation in which 48 mice were randomly designated into 6 groups of 8 each including: control, dexamethasone as positive control (15 mg/kg), and experimental groups (42, 85, 170, and...

We aimed to study phytochemical screening and analgesic activity of ethanol extract of Oroxylum indicum. The dried powder of the barks of the plant was extracted with 95% ethanol and was subjected to various phytochemical tests to ascertain the principle constituents contained in the extract. The result revealed the presence of alkaloids, flavonoids, tannins, glycosides in the ethanol extract o...

Anthranylic acid derivatives are direct structural analogs of salicylic acid derivatives. They possess analgesic, anti-inflammatory, and antipyretic activity. They are similar to pyrazolones in terms of analgesic and antipyretic activity, yet they exceed the anti-inflammatory activity of salicylates. The mechanism of action of this series of nonsteroid, anti-inflammatory analgesics is not concl...

Derivatives of pyridine-4-one are iron chelators with various biological activities including antifungal, anti-malarial, antiviral, anti-inflammatory and analgesic activities. This study was aimed to evaluate the analgesic effect of four new derivatives of 3-hydroxy pyridine-4-one in animal models. Acetic acid-induced writhing and formalin tests were used to assess the analgesic activity in mal...

The noradrenalin and serotonin re-uptake inhibitor venlafaxine has an analgesic eŠect that is independent of its antidepressant activity; however, the mechanism of this eŠect remains to be elucidated. This study was performed to investigate the possible roles of the opioidergic system and nitric oxide (NO) pathway in the analgesic eŠect of venlafaxine. Eighty Wistar rats of both sexes were allo...

Conium maculatum Linn. (Umbelliferae) has been traditionally used in the treatment of spasmodic disorders, and to relieve nervous excitation, rheumatic pains in the old and feeble, pain in stomach, pain of gastric ulcer, nervousness and restlessness. Alkaloids have long been considered as bioactive group of constituents present in C. maculatum. Despite a long tradition of use, C. maculatum has ...

Commercially available Aztec marigold (Tagetes erecta) flower extract (Af.Cr) was evaluated for the in vitro antioxidant activity and in vivo analgesic effect on acetic-acid-induced abdominal writhing. The results revealed the presence of pronounced antioxidant potential in Aztec marigold flowers and a dose-dependent (100 and 300 mg/kg) analgesic effect. The antioxidant and analgesic activities...

The anti-inflammatory and analgesic activity of various extracts of Ficus glomerata Roxb. were evaluated in experimental animals. We have determined the anti-inflammatory and analgesic activity of various extracts of the dried fruits of Ficus glomerata by oral administration at doses of 200 and 400 mg/kg of body weight to healthy animals. The extracts were studied for their anti-inflammatory ac...

The general method for synthesis the eta(6)-(arene)-triscarbonyl-chromium(0) complexes was modified and applied for preparation of eta(6)-(anisole)-triscarbonyl-chromium(0) and the study of its analgesic activity was undertaken. A significant analgesic activity was observed after intraperitoneal injection, in Wistar rats. Two doses (30 and 50 mg/Kg of the body weight) of eta(6)-(anisole)- trisc...