Background Epidural analgesia has become the standard of care for knee replacement surgeries worldwide. Bupivacaine has been used successfully for many years. Epidural ropivacaine is now being used increasingly and seems to have benefits other than just pain relief, in terms of a better safety profile. Aim To compare the efficacy of bupivacaine 0.125% (Group B) versus two concentrations of ro...

Methods. In a prospective double-blind, randomized, placebo-controlled study, we investigated the analgesic effect of a single dose of parecoxib 40 mg given at dural closure in 82 patients undergoing elective craniotomies. Remifentanil was used intraoperatively, and i.v. morphine was titrated to the requirement in the post-anaesthetic unit. On the ward, i.m. morphine 5 mg as required and regula...

As a result of it does not need a wide laparatomy incision and a minimal dissection made only in the part of stomach, advantages of this technique are not only less operation time, less postoperative pain, ileus and wound side complication but also less postoperative analgesic requirement, applicability in accordance with regional anesthesia, less duration of hospital state and it provides oppo...

A randomized study was performed to assess the effect of topical 1% amethocaine hydrochloride on postoperative analgesia requirements after strabismus surgery. Forty children scheduled for elective operation were allocated randomly to receive either topical amethocaine or normal saline. Postoperative analgesia was evaluated with the use of a four-point assessment score and analgesic requirement...

INTRODUCTION Septoplastical surgery to correct septum deviation can be performed under either local or general anesthesia. During local anesthesia, sedation helps to provide minimum anxiety/discomfort. Our aim was to evaluate the effects of patient-controlled analgesia using dexmedetomidine and propofol on sedation level, analgesic requirement, and patient satisfaction. STUDY DESIGN A prospec...

background: this double-blinded, randomized clinical trial was designed to evaluate the comparison of intravenous versus intraarticular (ia) administration of midazolam on postoperative pain after knee arthroscopy. materials and methods: in this study, 75 patients randomized in three groups to receive 75 mc/kg ia injection of midazolam and 10 ml intravenous injection of isotonic saline (group i...

Introduction: The aim of this study was to evaluate the preemptive analgesic effect and duration of postoperative analgesia after caudal blocks in children. Methods: Forty-five children who underwent distal hypospadias surgery were assigned to group one (n=23) received caudal bupivacaine (0.25%) 0.5 mg kg-1 and midazolam 0.05 mg kg-1 before the surgical incision, and group two (n=22) who receiv...

1 Professor Department of General Surgery, 2 Professor Department of Obstetrics and Gynecology, 3 Postgraduate Department of General Surgery, IMCHRC, Indore, M.P. INDIA *Corresponding Author Ashish Agrawal Email: [email protected] Abstract Background:-Cholecystectomy is now widely practised. There are various methods of pain relief. Aim of our study is to asscess the analgesic effect of ...

OBJECTIVE To systematically analyze the role of heated humidified carbon dioxide (CO2) in laparoscopy. METHODS Clinical trials on laparoscopic procedures using standard dry CO2 versus heated humidified CO2 for pneumoperitoneum were analyzed. RESULTS Ten randomized controlled trials on 565 patients were analyzed. In both the fixed and random effect models, postoperative pain was significantl...

BACKGROUND Both central sensitization after peripheral tissue injury and the development of opioid tolerance involve activation of N-methyl-D-aspartate (NMDA) receptors. At subanesthetic doses the NMDA receptor antagonist xenon suppresses pain-evoked sensitization of pain-processing areas in the central nervous system. Although numerous studies describe the effect of NMDA receptor antagonists o...