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The article presents the results of a survey Russian oceanographers regarding need for data on physical, biogeochemical and biological state Black Azov Seas in order to form requirements creation an online platform System Systems (SoS) based modern tools, observations, modeling integration, performed according stakeholder methodology electronic questionnaire developed within framework internati...
OBJECTIVE Nonexperimental survey and field research support the notion that alcohol use may be associated with deliberate self-harm (DSH) across the spectrum of lethality, from nonsuicidal self-injury (NSSI) through suicide. Nonexperimental studies, however, provide limited information about potential causal relationships between alcohol consumption and DSH. Two previous experiments showed that...
Intratumor heterogeneity (ITH) contributes to cancer progression and chemoresistance. We sought to comprehensively describe ITH of somatic mutations, copy number, and transcriptomic alterations involving clinically and biologically relevant gene pathways in colorectal cancer (CRC). We performed multiregion, high-depth (384× on average) sequencing of 799 cancer-associated genes in 24 spatially s...
Gorlin syndrome is an autosomal dominant disorder characterized by tumor preponderance and developmental defects. Diagnosis traditionally made based on clinical criteria, including the presence of major features, such as multiple basal cell carcinomas (BCCs), palmar plantar pits, jaw keratocysts, falcine calcification, well minor skeletal radiologic abnormalities. predominantly caused mutations...
La finalidad del presente estudio es determinar el tamaño de las nanopartículas óxido zinc (NPs-ZnO), sintetizadas por método la precipitación química a partir reacción entre acetato e hidróxido sodio. Se realizó respectiva caracterización difracción rayos X (DR-X), los resultados obtenidos este instrumental corresponden estructura zincita (ZnO) sistema hexagonal, cuyos datos estructurales cris...
Abstract Introduction The use of recreational substances in a sexual context (sex-linked substance use) is common among young adults, with up to third indicating that they used alcohol, cannabis, or both during their recent partnered activity (Willis et al., 2021; Herbenick 2018). Sex-linked (SLSU) associated variety positive and negative clinical outcomes including increased pleasure, but also...
Abstract Background During sepsis, neutrophils, upon activation, undergo biophysical and biochemical changes that may terminate in the release of neutrophil extracellular traps (NETs) (1–3). The IntelliSep test is a rapid sepsis diagnostic assesses immune activation by quantifying properties leukocytes from whole blood <10 minutes. results Index (ISI), ranging between 0.1–10.0, stratifie...
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