Introduction: Blood loss is a common concern during functional endoscopic sinus surgery (FESS). The present study aimed to evaluate the efficacy of dexmedetomidine (DEX) in intraoperative bleeding and surgical field in FESS.   Materials and Methods: This double-blind randomized clinical trial was conducted on 72 patients within the age range of 16-60 years who underwent ...

This article examines how courts are likely to apply evidence-based medicine, and particularly clinical practice guidelines (CPGs), in healthcare litigation involving quality-of-care and entitlement-to-benefits (coverage) claims. Exploring the "politics" of the current situation, it observes that, just as clinicians have been reluctant to use CPGs in practice, courts have been, and likely will ...

OBJECTIVES To measure eligibility for medical thromboprophylaxis using two Australasian guidelines - the Australia and New Zealand Working Party Guidelines [WPG] and the National Health and Medical Research Council Guidelines [NHMRCG]) - and proposed new guidelines based on risk-factor weights; and to measure the incidence of clinical venous thromboembolism (VTE) events in medical patients ("en...

The history of therapeutic hypothermia (TH) dates back to Hippocrates. He advocated packing of wounded soldiers into snow and ice. In modern clinical medicine TH has been practiced for the last 200 years mostly in operating rooms. Pathophysiological basis of TH as a neuro-protective method is based on slowing of cellular metabolism secondary to decrease in body temperature. For every one degree...

a Department of Family Practice, Virginia Commonwealth University, Fairfax, Virginia 22033, USA, b Center for Quality of Care Research, University of Nijmegen, PO Box 9101, 6500 HB Nijmegen, Netherlands, c School of Health and Related Research, University of Sheffield, Sheffield S1 4DA, d Centre for Health Services Research, University of Newcastle upon Tyne, Newcastle upon Tyne NE2 4AA, e Heal...