In this article we present an approach for tackling three important aspects of text normalization: sentence boundary disambiguation, disambiguation of capitalized words in positions where capitalization is expected, and identification of abbreviations. As opposed to the two dominant techniques of computing statistics or writing specialized grammars, our document-centered approach works by consi...

The immune microenvironment is considered a major obstacle to generating an effective antitumor immune response. Checkpoint inhibitors manipulate the co-stimulatory response between antigen-presenting cells and immune cells-or between the tumor and immune cells-to elicit an antitumor immune response that would have otherwise been suppressed. Checkpoint inhibitors have shown great promise in the...